Arachidonic Acid and strength & muscle

What 3 graded rows on arachidonic acid agree on for strength & muscle, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Arachidonic Acid page, with its PubMed record.

Your question

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Arachidonic Acid and strength & muscle

3 rows · 80 people

Mostly no difference: 2 of 3 rows, and most of the people. 1 found an improvement.

No difference
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside.
  • Grade D× 3
Rows
3
Trials
3
People
80

Where they differ

From the rows
How long

The best-graded row, grade D, is a randomized trial of 31 people (2007) and found no difference.

The row that found an improvement ran longer (8 weeks) than the 2 rows that found no difference (4 to 7 weeks).

The rows

1 improved · 2 no difference
  1. Grade DStrength, body composition and anaerobic power during resistance training · No difference

    RCT · n 31 · 2007 · Resistance-trained men (15 ARA, 16 placebo)

    1 g/day · 50 days

    Wingate relative peak power was higher after 50 days and IL-6 was lower at day 25 in the ARA group, but there were no significant differences versus placebo in body composition, strength, anabolic or catabolic hormones, or markers of muscle hypertrophy.

    Row on the Arachidonic Acid page · PubMed 18045476 (opens PubMed)

  2. Grade DMuscle protein synthesis and anabolic signalling after resistance exercise · No difference

    RCT · n 19 · 2018 · Resistance-trained men (at least 1 year of training)

    1.5 g/day · 4 weeks, then one resistance-exercise session

    Muscle protein synthesis over 4 hours of recovery did not differ from placebo (P = 0.212), and neither did mTOR signalling or the rise in satellite cells; a ribosome-biogenesis marker (45S pre-rRNA) rose at 48 hours only with ARA.

    Row on the Arachidonic Acid page · PubMed 29389245 (opens PubMed)

  3. Grade DLean mass, strength and power during 8 weeks of strength training · Improved

    RCT · n 30 · 2016 · Strength-trained young men (mean age 20)

    Not stated in the abstract · 8 weeks

    Lean body mass (+2.9%), upper-body strength (+8.7%) and peak power (+12.7%) increased only in the ARA group.

    Row on the Arachidonic Acid page · PubMed 27182886 (opens PubMed)

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