Apigenin and anxiety
What 2 graded rows on apigenin agree on for anxiety, and where they differ. Counted side by side, never averaged.
Consensus finder Rows from the Apigenin page, reviewed Oct 21, 2026 How it decides
What the rows agree on
Each block and row is one graded row from the Apigenin page, with its PubMed record.
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Apigenin and anxiety
2 rows · 150 peopleSplit. 1 row found an improvement and 1 had mixed results.
- DGrade D× 2
- Rows
- 2
- Trials
- 2
- People
- 150
What the rows share
From the rowsThe best-graded row, grade D, is a randomized trial of 93 people (2016) and reported mixed results.
The rows run from 57 to 93 people, published from 2009 to 2016: 2 single studies.
The rows
1 improved · 1 mixed- DGrade DAnxiety symptoms in generalized anxiety disorder (chamomile extract) · Improved
RCT · n 57 · 2009 · Outpatients with mild to moderate generalized anxiety disorder (USA)
Escalating dose (amounts not stated in the abstract) · 8 weeks
Hamilton Anxiety scores fell more than with placebo (P=0.047); secondary measures moved in the same direction.
- DGrade DRelapse and symptoms during long-term chamomile use in anxiety · Mixed
RCT · n 93 · 2016 · Responders to 12 weeks of open-label chamomile with moderate-to-severe generalized anxiety disorder (USA)
1,500 mg/day (500 mg three times daily) · 26 weeks randomized continuation
Relapse was not significantly reduced (hazard ratio 0.52, P=0.16), but anxiety symptoms stayed lower than after switching to placebo (P=0.0032).