Amla and blood pressure

What 2 graded rows on amla agree on for blood pressure, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Amla page, with its PubMed record.

Your question

Amla and blood pressure

2 rows · 231 people

Split. 1 row found an improvement and 1 found no difference.

No difference
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside.
  • Grade C× 1
  • No effect× 1
Rows
2
Trials
2
People
231

Where they differ

From the rows
How longWhen published

The best-graded row, grade C, is a randomized trial of 81 people (2020) and found an improvement. 1 row is graded No effect, our grade for adequately powered trials that found no effect.

The row that found no difference ran longer (3 months) than the row that found an improvement (8 weeks).

The row that found no difference is newer (2021) than the row that found an improvement (2020).

The rows

1 improved · 1 no difference
  1. Grade CBlood pressure as add-on to blood pressure medicines · Improved

    RCT · n 81 · 2020 · Adults with uncontrolled hypertension on standard drugs (Iran)

    500 mg three times daily (1,500 mg/day) · 8 weeks

    Systolic pressure fell 15.6% vs 6.3% with placebo and diastolic 12.3% vs 3.9% (both P<0.001). No side effects were reported.

    Row on the Amla page · PubMed 33082832 (opens PubMed)

  2. No effectBlood pressure as add-on to blood pressure medicines · No difference

    RCT · n 150 · 2021 · Adults with essential hypertension on their usual medicines

    500 mg twice daily (1,000 mg/day) · 12 weeks

    No additional fall in systolic or diastolic pressure versus placebo, and no improvement in lipids, HbA1c, hs-CRP, oxidative markers or arterial stiffness; safety was good.

    Row on the Amla page · PubMed 33570228 (opens PubMed)

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