Mineral

Boron

Also called calcium fructoborate, boron citrate, boron glycinate

By Kymata Labs EditorialMedical review pendingLast reviewed October 11, 2026 · What changed

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Summary

Boron is a trace element in plant foods that is not classed as an essential nutrient. Small trials suggest less menstrual pain and possible effects on osteoarthritis symptoms and sex hormones, but evidence is thin. The adult upper limit is 20 mg/day, and very large doses are toxic. ODS lists no known medicine interactions.

Top graded outcomes:C evidence grade Menstrual pain severity and durationD evidence grade Sex hormones and inflammation markers

Key facts

Essential?
No RDA or AI; boron is not classed as essential because no clear biological function has been identified[1]
Upper limit
20 mg/day for adults, including pregnancy and lactation; WHO estimates a safe range of 1–13 mg/day[1]
Food sources
Prune juice (1.43 mg per cup), avocado (1.07 mg per ½ cup), raisins and peaches; coffee, milk and apples are main US sources[1]
Osteoarthritis
Two small 8-week studies of 20 people each reported fewer symptoms at 6 mg/day (12 mg/day for severe disease in one, which was not blinded or placebo-controlled); ODS says confirmation is needed[1]
Absorption
About 85–90% of ingested boron is absorbed; it concentrates in bone, nails and hair[1]
Evidence base
2 graded human outcomes on this page
Last reviewed
October 11, 2026

How it works

ProposedBoron may influence bone formation, inflammation and steroid hormones including vitamin D and estrogen, but a clear biological role in humans has not been identified.[1]

What the human research says

Human trials only, one row per outcome. The form column shows what each trial actually tested. Grades follow our evidence-grading policy.

At a glance: strongest evidence per outcome

Evidence at a glance: strongest human evidence per outcome
OutcomeGradeEffectStrongest evidenceRows
Menstrual painGrade CImprovedRCT · n = 113 · 2015Form tested: Boron capsules1 row
HormonesGrade DMixedOpen-label · n = 8 · 2011Form tested: Boron capsules1 row

Every graded row

Outcome
Grade
Sort

Showing 2 of 2 outcomes. Human trials only.

OutcomeEffectGradeBest evidencePMID
Menstrual pain severity and durationImprovedGrade C

RCT · n = 113 · 2015

University students with primary dysmenorrhea

Form: Boron capsules · Dose: 10 mg/day from 2 days before to day 3 of menstruation · Duration: 2 menstrual cycles

Pain severity and duration were lower than with placebo after the intervention.

25906949 (opens PubMed)Source [2]
Sex hormones and inflammation markersMixedGrade D

Open-label trial · n = 8 · 2011

Healthy men

Form: Boron capsules · Dose: 10 mg/day · Duration: 1 week

Free testosterone rose and estradiol fell after a week, and SHBG, hsCRP and TNF-α fell within hours; there was no placebo group and only 8 participants.

21129941 (opens PubMed)Source [3]

Forms

FormElemental %Absorption (human data)GI toleranceStudied for
Calcium fructoborateVariesLabels usually state elemental boron per servingMost ingested boron, whatever the form, is converted to boric acid in the gut and 85–90% is absorbed.[1]No form-specific tolerance data in the sources cited here.Osteoarthritis pilot studies
Boron citrate, glycinate or aspartateVariesLabels usually state elemental boron per servingNo head-to-head human data comparing forms in the sources cited here.No form-specific tolerance data in the sources cited here.General supplements

Studied doses

Doses studied in human trials ranged from 1.5–6 mg of boron per day for 2 weeks (calcium fructoborate) and 3 mg per day for 10 months (bone markers) to 6–12 mg per day in 8-week osteoarthritis studies and 10 mg per day in hormone and menstrual-pain studies; the adult UL is 20 mg per day.[1][2][3]

Intake reference: No RDA, AI or EAR. Tolerable Upper Intake Level: 20 mg/day for adults 19 and older (including pregnancy and lactation); 17 mg/day at 14–18 years.[1] ULs for children are lower (3 mg at 1–3 years, 6 mg at 4–8 years, 11 mg at 9–13 years); infants should get boron only from breast milk, formula and food. NIH ODS fact sheet (updated June 9, 2022).

These are amounts used in research, not personal advice. Your clinician or pharmacist can say what fits you.

Interactions

Published interactions only: each row cites a source. No row means none was found in our sources, not that a combination is safe.

None found in our sources.

Who should be careful

High doses
Boric acid or borax poisoning causes nausea, vomiting, diarrhea, rash and convulsions; 15,000–20,000 mg can be fatal in adults. Supplements should stay under the 20 mg/day UL.[1]
Children
ULs are much lower for children (3–11 mg/day), and infants should get boron only from food, breast milk or formula.[1]

Talk to your pharmacist or clinician before starting a supplement, especially if you take prescription medicines.

Food sources

FoodServingAmount
Prune juice1 cup1.43 mg[1]
Avocado, raw, cubed½ cup1.07 mg[1]
Raisins1.5 ounces0.95 mg[1]
Peach1 medium0.8 mg[1]
Apple1 medium0.66 mg[1]
Foods by boron per serving
  • Prune juice1 cup1.4 mg
  • Avocado, raw, cubed½ cup1.1 mg
  • Raisins1.5 ounces1 mg
  • Peach1 medium0.8 mg
  • Apple1 medium0.7 mg

Frequently asked questions

Is boron an essential nutrient?

No. There is no RDA because a clear biological function in humans has not been identified.[1]

How much boron is too much?

The adult upper limit is 20 mg/day; very large accidental doses of boric acid are toxic and can be fatal.[1]

Does boron raise testosterone?

In 8 healthy men, 10 mg/day for a week raised free testosterone and lowered estradiol, but there was no placebo group.[3]

Does boron help joint pain?

Two small 8-week studies of 20 people each reported improvements at 6 mg/day, one without a placebo group; short calcium fructoborate trials also eased knee discomfort, but ODS says confirmation is needed.[1]

Does boron interact with medicines?

ODS lists no known clinically relevant interactions with medications.[1]

Sources

  1. [1]Boron: Fact Sheet for Health Professionals. NIH Office of Dietary Supplements, 2022. fact-sheet
  2. [2]Effects of boron supplementation on the severity and duration of pain in primary dysmenorrhea. Complement Ther Clin Pract, 2015. RCT PMID 25906949
  3. [3]Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines. J Trace Elem Med Biol, 2011. open-label PMID 21129941

What changed

  1. October 11, 2026 · all · new page (encyclopedia expansion, A–L)New monograph. Every PMID checked against NCBI E-utilities (title, journal and year from the PubMed record); each evidence row written from its abstract; intake and safety facts from the cited fact sheets.Writer: Kymata Labs Editorial · No credentialed reviewer yet
  2. October 11, 2026 · all · Independent pre-publication reviewReview: osteoarthritis lines now state that one pilot was unblinded with no placebo, matching the ODS fact sheet; dose range widened to the 1.5 mg/day trial ODS describes.Writer: Kymata Labs Editorial · No credentialed reviewer yet

How we write, grade and correct these pages: editorial and evidence policy.

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