Arnica

Also called Arnica montana, mountain arnica, leopard's bane, arnica gel, homeopathic arnica.

The short answer

From 29 sources

Arnica is sold as herbal gels and creams for sore joints, bruises and muscles, and as homeopathic pills. An arnica gel matched ibuprofen gel for hand osteoarthritis in one 204-person trial (grade B), but creams did not reduce bruising after eyelid surgery, and homeopathic arnica trials are mixed. Arnica can cause contact allergy and is toxic by mouth as an herb.

Key facts

Two different products
Herbal arnica (gels, creams, tinctures made from the flowers) and homeopathic arnica (pills diluted as far as 1:10^30) share a name but not a dose314
Strongest human evidence
Hand osteoarthritis (B): an arnica gel was not inferior to 5% ibuprofen gel for pain and hand function over 21 days in 204 people; Cochrane rated the evidence moderate54
Bruising
10% arnica ointment did not improve swelling, bruising or appearance after upper eyelid surgery in 136 patients, and an arnica gel did not change laser bruises in 1989
Muscle soreness
Mixed: topical arnica increased leg pain 24 hours after calf exercise in 53 people, and eased tenderness only at 72 hours after downhill running in 20 trained men67
Homeopathic arnica
A 1998 systematic review found no good evidence it beats placebo; a 2021 meta-analysis of surgery trials found a small effect that just missed significance against placebo (g = 0.18, p = 0.059)1112
Allergy
About 1.1% of 443 dermatology patients reacted to arnica on patch testing; its sesquiterpene lactones (such as helenalin) are the main sensitizers1920211
Not by mouth
NIH's LactMed says oral botanical arnica should be avoided because of its many toxic components; US rules allow arnica flowers as a flavouring only in alcoholic beverages32

What it is

Arnica (Arnica montana) is a daisy-family plant used in skin gels and creams and as highly diluted homeopathic pills; the herb is not for eating.

How it works

Proposed

Arnica flowers contain flavonoid glycosides, terpenoids, amines, coumarins and volatile oils, and sesquiterpene lactones such as helenalin and its esters. The sesquiterpene lactones are the main cause of the allergic and irritant skin reactions arnica can provoke. How a topical arnica gel would ease joint pain is not established in the sources here. Homeopathic preparations are serial dilutions, for example 30x (1:10^30), and NCCIH finds little evidence that homeopathy works for any specific condition.3202111413

Forms side by side: gel, ointment, homeopathic pills and the herb

4 forms named in our sources. The rest show what our data holds, and say plainly where it holds nothing yet.

Arnica forms compared

4 forms
Arnica forms compared: 4 forms by 3 attributes. Empty cells are labelled No data yet, or Not graded in the evidence row.
4 formsGel (tincture-based)Ointment or cream (10% to 20%)Homeopathic arnica pills or globules (6C, 30C, 30x, D30)Tea, tincture or herb taken by mouth
Absorption in peopleApplied to the skin over the painful joint; no human data on how much is absorbed.5Applied to intact skin; no human absorption data.8Taken by mouth as highly diluted pills (30x is 1:10^30); NCCIH notes that some products labelled homeopathic contain substantial amounts of active ingredients.1413Not studied in people for any benefit.3
ToleranceAdverse events in 4.8% vs 6.1% with ibuprofen gel in the hand trial; arnica can cause contact allergy.519LactMed says arnica should not be used on broken skin and may cause allergic skin reactions.3Adverse events did not differ from placebo in a hand-surgery trial; one rhinoplasty patient had itching and rash.1722LactMed says oral botanical arnica should be avoided because of its many toxic components; maternal arnica tea probably caused haemolytic anaemia in one breastfed infant.3
Studied forHand osteoarthritis (B); bruising (no effect)Bruising after eyelid surgery (no effect); muscle soreness (mixed, D)Soreness and recovery after running and surgery (mixed; C to no effect)Not graded: unsafe by mouth
  1. Arnica gel (tincture-based)
    Absorption in people
    Applied to the skin over the painful joint; no human data on how much is absorbed.5
    Tolerance
    Adverse events in 4.8% vs 6.1% with ibuprofen gel in the hand trial; arnica can cause contact allergy.519
    Studied for
    Hand osteoarthritis (B); bruising (no effect)
  2. Arnica ointment or cream (10% to 20%)
    Absorption in people
    Applied to intact skin; no human absorption data.8
    Tolerance
    LactMed says arnica should not be used on broken skin and may cause allergic skin reactions.3
    Studied for
    Bruising after eyelid surgery (no effect); muscle soreness (mixed, D)
  3. Homeopathic arnica pills or globules (6C, 30C, 30x, D30)
    Absorption in people
    Taken by mouth as highly diluted pills (30x is 1:10^30); NCCIH notes that some products labelled homeopathic contain substantial amounts of active ingredients.1413
    Tolerance
    Adverse events did not differ from placebo in a hand-surgery trial; one rhinoplasty patient had itching and rash.1722
    Studied for
    Soreness and recovery after running and surgery (mixed; C to no effect)
  4. Arnica tea, tincture or herb taken by mouth
    Absorption in people
    Not studied in people for any benefit.3
    Tolerance
    LactMed says oral botanical arnica should be avoided because of its many toxic components; maternal arnica tea probably caused haemolytic anaemia in one breastfed infant.3
    Studied for
    Not graded: unsafe by mouth
Every cell holds data from a cited page; citation numbers link to the page that holds them.Scroll the table for every column

What the human research says

Human trials only, one row per outcome. The form line shows what each trial actually tested. Grades follow our evidence-grading policy.

Trial map

14 graded outcomes, largest study first

14 graded outcomes: 3 improved, 5 mixed, 4 no effect, 2 worsened. The largest, a 2001 observational study of 443 people on contact allergy to arnica in dermatology patients, found a worsening. One other outcome found a worsening: leg pain after calf-raise exercise (topical cream) (53 people).

1Contact allergy to arnica in dermatology patients

Worsened · Grade D · Observational, 443 people, 2001

Consecutive patients patch-tested at a dermatology clinic

Dose, result and source
Every graded outcome on this page, largest study first
OutcomeFoundPeopleStudyWho was studied
Contact allergy to arnica in dermatology patientsWorsened443Grade D · Observational, 2001Consecutive patients patch-tested at a dermatology clinic
Muscle soreness after long-distance running (homeopathic 30x)No effect400No-effect grade · RCT, 1998Runners expecting delayed-onset soreness after long-distance races (519 randomized)
Knee swelling after knee surgery (homeopathic 30x, three trials)Mixed319Grade C · RCT, 2006Patients having arthroscopy (227), knee replacement (35) or cruciate ligament reconstruction (57)
Hand osteoarthritis pain and function: arnica gel vs ibuprofen gelImproved204Grade B · RCT, 2007Adults with radiologically confirmed, symptomatic osteoarthritis of the finger joints
Bruising, swelling and appearance after upper eyelid surgeryNo effect136No-effect grade · RCT, 2016Patients having bilateral upper blepharoplasty, with one untreated eyelid as internal control
Muscle soreness after a marathon (homeopathic D30, pooled)Improved82Grade C · Meta-analysis, 2003Marathon runners from two randomized placebo-controlled trials (Oslo Marathon 1990 and 1995)
Pain, bruising and swelling after carpal tunnel surgery (homeopathic)No effect62Grade D · RCT, 2003Adults having elective carpal tunnel surgery
Pain, swelling and jaw stiffness after wisdom tooth surgery (topical)Improved60Grade D · RCT, 2024Patients (mean age 27) having impacted lower third molars removed
Leg pain after calf-raise exercise (topical cream)Worsened53Grade D · RCT, 201053 subjects doing a standard calf-raise protocol, one leg arnica and one leg placebo
Recovery after carpal tunnel release (pills plus ointment)Mixed37Grade D · RCT, 2002Patients having bilateral endoscopic carpal tunnel release
Bruising after face-lift surgery (homeopathic)Mixed29Grade D · RCT, 2006Patients having rhytidectomy at a tertiary care centre
Bruising after rhinoplasty (oral arnica)Mixed22Grade D · RCT, 2016Patients having rhinoplasty with nasal bone osteotomies by one surgeon (9 arnica, 13 placebo)
Muscle soreness and recovery after downhill running (topical)Mixed20Grade D · RCT, 2014Well-trained men with delayed-onset muscle soreness
Laser-induced facial bruising (topical gel)No effect19Grade D · RCT, 2002Patients with facial telangiectases treated with a pulsed dye laser
Each circle is one graded outcome on this page, numbered from the largest study down, and placed by how many people it studied (log scale). It shows who was studied and what was found, not advice about your dose.

Every graded row

14 rows

Showing 14 of 14 outcomes. Human trials only.

Grade BHand osteoarthritis pain and function: arnica gel vs ibuprofen gelJointsNot inferior to ibuprofen gelRCT
n 204 · 2007

Improved Pain and hand function improved equally in both groups, with no differences in any secondary endpoint, so arnica gel was judged not inferior to ibuprofen gel. Adverse events: 4.8% with arnica, 6.1% with ibuprofen.

Design
RCT, n = 204, 2007
Population
Adults with radiologically confirmed, symptomatic osteoarthritis of the finger joints
Form
Arnica gel (50 g tincture per 100 g, DER 1:20) vs 5% ibuprofen gel
Dose
Topical gel as directed in the trial
Duration
21 days
Source
Reference 5 · PubMed 17318618 (opens PubMed)
Grade CKnee swelling after knee surgery (homeopathic 30x, three trials)After surgerySignificant in 1 of 3 trialsRCT · 3 studies
n 319 · 2006

Mixed All three trials showed a trend toward less swelling, but the difference was significant only after ligament reconstruction (−1.80%, 95% CI −3.30 to −0.30); arthroscopy and knee replacement showed no significant difference.

Design
RCT, 3 studies, n = 319, 2006
Population
Patients having arthroscopy (227), knee replacement (35) or cruciate ligament reconstruction (57)
Form
Homeopathic Arnica 30x globules vs placebo
Dose
5 globules before surgery, then 5 globules three times a day
Duration
Until day 1 or 2 after surgery (primary outcome)
Source
Reference 14 · PubMed 17105693 (opens PubMed)
Grade CMuscle soreness after a marathon (homeopathic D30, pooled)Muscle sorenessLess soreness (P = 0.04)Meta-analysis · 2 studies
n 82 · 2003

Improved Soreness right after the marathon was lower with arnica (P = 0.04); muscle enzymes, a measure of cell damage, did not differ.

Design
Meta-analysis, 2 studies, n = 82, 2003
Population
Marathon runners from two randomized placebo-controlled trials (Oslo Marathon 1990 and 1995)
Form
Homeopathic Arnica D30 pills vs placebo
Dose
Five pills morning and evening
Duration
From the evening before the race to 3 days after
Source
Reference 16 · PubMed 14587684 (opens PubMed)
Grade DContact allergy to arnica in dermatology patientsSkin allergy1.13% sensitizedObservational
n 443 · 2001

Worsened 5 of 443 (about 1.13%) reacted to arnica and 9 to marigold; testing with the Compositae or sesquiterpene lactone mix alone missed some arnica allergies.

Design
Observational, n = 443, 2001
Population
Consecutive patients patch-tested at a dermatology clinic
Form
Arnica extract patch test
Dose
Patch test
Duration
Single test series
Source
Reference 19 · PubMed 11722485 (opens PubMed)
Grade DPain, bruising and swelling after carpal tunnel surgery (homeopathic)After surgeryNo difference vs placeboRCT
n 62 · 2003

No effect Pain (P = 0.79) and bruising (P = 0.45) at day 4 did not differ from placebo, nor did swelling or painkiller use.

Design
RCT, n = 62, 2003
Population
Adults having elective carpal tunnel surgery
Form
Homeopathic arnica 30C or 6C tablets vs placebo
Dose
Three tablets a day
Duration
7 days before and 14 days after surgery
Source
Reference 17 · PubMed 12562974 (opens PubMed)
Grade DPain, swelling and jaw stiffness after wisdom tooth surgery (topical)Oral surgery recoveryLess pain to day 5; swelling unchangedRCT
n 60 · 2024

Improved Pain scores were lower than with standard therapy alone up to day 5, and limited mouth opening (trismus) was smaller on days 1, 3 and 5 (P < .05); facial swelling was not reduced by arnica.

Design
RCT, n = 60, 2024
Population
Patients (mean age 27) having impacted lower third molars removed
Form
Topical arnica added to standard therapy (antibiotic plus NSAID) vs standard therapy alone; a third arm used mucopolysaccharide polysulfate
Dose
Topical application (amount not stated in the abstract)
Duration
Measured on days 1, 3, 5 and 10 after surgery
Source
Reference 25 · PubMed 37913818 (opens PubMed)
Grade DLeg pain after calf-raise exercise (topical cream)Muscle sorenessMore pain at 24 h (3.04 vs 2.36)RCT
n 53 · 2010

Worsened Pain scores 24 hours after exercise were higher on arnica-treated legs than on placebo legs (3.04 vs 2.36, p < 0.005); there was no difference at days 3 and 4, and muscle tenderness and ankle range of motion did not differ.

Design
RCT, n = 53, 2010
Population
53 subjects doing a standard calf-raise protocol, one leg arnica and one leg placebo
Form
Topical arnica cream vs placebo cream
Dose
Applied right after exercise and at 24 and 48 hours
Duration
4 days
Source
Reference 6 · PubMed 20807867 (opens PubMed)
Grade DRecovery after carpal tunnel release (pills plus ointment)After surgeryLess pain at 2 weeks onlyRCT
n 37 · 2002

Mixed Grip strength and wrist swelling did not differ, but pain at 2 weeks was significantly lower in the arnica group (P < .03).

Design
RCT, n = 37, 2002
Population
Patients having bilateral endoscopic carpal tunnel release
Form
Homeopathic arnica tablets plus herbal arnica ointment vs placebos
Dose
As directed in the trial
Duration
2 weeks
Source
Reference 23 · PubMed 11892685 (opens PubMed)
Grade DBruising after face-lift surgery (homeopathic)BruisingSmaller bruise area on 2 of 4 daysRCT
n 29 · 2006

Mixed Patients and staff saw no difference, and colour change did not differ; the bruised area was smaller with arnica, significantly so on 2 of 4 days measured.

Design
RCT, n = 29, 2006
Population
Patients having rhytidectomy at a tertiary care centre
Form
Homeopathic Arnica montana vs placebo
Dose
Perioperative, as directed in the trial
Duration
Up to postoperative day 10
Source
Reference 18 · PubMed 16415448 (opens PubMed)
Grade DBruising after rhinoplasty (oral arnica)BruisingSmaller bruises (P < 0.1 threshold)RCT
n 22 · 2016

Mixed Bruise extent was 16% to 33% smaller with arnica, with significance claimed on day 7 using a P < 0.1 threshold (P = 0.097); intensity differences were mixed. One person had itching and rash.

Design
RCT, n = 22, 2016
Population
Patients having rhinoplasty with nasal bone osteotomies by one surgeon (9 arnica, 13 placebo)
Form
Oral perioperative Arnica montana vs placebo
Dose
Perioperative, as directed in the trial
Duration
Measured on postoperative days 2/3, 7 and 9/10
Source
Reference 22 · PubMed 25954844 (opens PubMed)
Grade DMuscle soreness and recovery after downhill running (topical)Muscle sorenessLess pain at 72 h onlyRCT
n 20 · 2014

Mixed The arnica group reported less pain and muscle tenderness 72 hours after the run. Arnica did not change strength or jump performance, or blood markers of muscle damage and inflammation.

Design
RCT, n = 20, 2014
Population
Well-trained men with delayed-onset muscle soreness
Form
Topical arnica vs placebo on thigh and calf muscles
Dose
Every 4 waking hours
Duration
96 hours
Source
Reference 7 · PubMed 23947690 (opens PubMed)
Grade DLaser-induced facial bruising (topical gel)BruisingNo difference vs vehicleRCT
n 19 · 2002

No effect Bruising scores did not differ between arnica and vehicle, whether the gel was used before (P = 0.496) or after (P = 0.359) laser treatment.

Design
RCT, n = 19, 2002
Population
Patients with facial telangiectases treated with a pulsed dye laser
Form
Arnica gel on one side of the face vs vehicle on the other
Dose
Twice a day
Duration
2 weeks before or 2 weeks after the laser
Source
Reference 9 · PubMed 12174058 (opens PubMed)
No effectMuscle soreness after long-distance running (homeopathic 30x)Muscle soreness45.2 vs 41.0 mm (n.s.)RCT
n 400 · 1998

No effect Mean 2-day soreness scores were 45.2 mm with arnica and 41.0 mm with placebo (95% CI 8.81 mm favouring placebo to 0.51 mm favouring arnica); race times did not differ.

Design
RCT, n = 400, 1998
Population
Runners expecting delayed-onset soreness after long-distance races (519 randomized)
Form
Homeopathic Arnica 30x pills vs indistinguishable placebo
Dose
As directed in the trial for 5 days
Duration
5 days after the race
Source
Reference 15 · PubMed 9758072 (opens PubMed)
No effectBruising, swelling and appearance after upper eyelid surgeryBruisingNo difference vs placeboRCT
n 136 · 2016

No effect There was no difference between arnica and placebo in overall appearance, swelling, bruising, redness, pain or satisfaction at any time point; untreated eyelids did as well as treated ones.

Design
RCT, n = 136, 2016
Population
Patients having bilateral upper blepharoplasty, with one untreated eyelid as internal control
Form
Arnica ointment 10% vs placebo ointment
Dose
Applied to one periorbital area after surgery
Duration
Assessed at 3 days, 7 days and 6 weeks
Source
Reference 8 · PubMed 27348641 (opens PubMed)

What the numbers add up to

Each point is worked out from the data and the sources numbered on this page, with the arithmetic shown under it. It adds no new data and is not medical advice.

Arnica gel vs ibuprofen gel in numbers

In Cochrane's analysis of the hand trial, pain differed by 3.8 points on a 100-point scale between the two gels, a 4% difference, while total adverse events were 13% with arnica and 8% with ibuprofen.4

How we got this: Cochrane 2013: MD −3.8 (95% CI −10.1 to 2.5); adverse events RR 1.65 (0.72 to 3.76)

The largest homeopathic trial was negative

The biggest single trial here, 400 runners, found homeopathic arnica 30x no better than placebo for soreness; smaller trials report mixed results.151422

How we got this: Vickers 1998 (n = 400) vs the other homeopathic rows (n = 22 to 319)

Topical arnica and soreness: two trials, two directions

In 53 people, legs given arnica hurt more 24 hours after exercise; in 20 trained men, arnica eased tenderness at 72 hours. Neither found an effect on performance or muscle damage markers.67

How we got this: Adkison 2010 and Pumpe 2014

Studied doses

Doses used in research, shown against the official limits. They describe the studies, not a recommendation for you.

Studied doses in research, not advice. These are amounts used in research, not personal advice. Your clinician or pharmacist can say what fits you.

Doses studied in human trials

Doses studied in human trials ranged from a single 10% ointment course after eyelid surgery and arnica gel twice a day for 2 weeks to a tincture-based gel used for 21 days on the hands and topical arnica every 4 waking hours for 4 days after running. Homeopathic trials used 6C, 30C, 30x or D30 pills, typically three to five pills one to three times a day from before surgery or a race until up to 2 weeks after. These are research regimens, not product directions.8957171416

When trials measured an effect

4 outcomes
How long trials ran before effects were measured
OutcomeMeasured atBasis
Hand osteoarthritis painMeasured at 21 daysRandomized comparison with ibuprofen gel5
Muscle soreness after runningLess pain at 72 hours, not earlierPlacebo-controlled trial in 20 trained men7
Bruising after eyelid surgeryNo difference at 3 days, 7 days or 6 weeksPlacebo-controlled trial in 136 patients8
Pain after wisdom tooth surgeryLower pain than standard care alone from day 1 up to day 5Randomized trial in 60 patients, without placebo25
When each outcome was assessed in the cited trials. It is not a promise of when anyone will notice a change.

Interactions and safety

Published interactions only: each row cites a source. No row means none was found in our sources, not that a combination is safe.

What Arnica meets

2 cited rows

Medicines 1

Arnica1 medicine · 1 supplement

Supplements and foods 1

  • Reference summary
Rows as our evidence profiles cite them; links stay on this site. Line weight shows what backs a row, not how serious an interaction is. No line means none was found in our sources, not that a combination is safe. Not medical advice: ask your pharmacist.

Interactions

2 agents
Published interactions, grouped by kind
AgentWhat the source saysEvidence
Medicines1
Warfarin and other blood thinnersA 2000 pharmacy review lists arnica flower among herbs that may raise bleeding risk or add to warfarin's effect, noting that nearly all herb-warfarin information comes from lab, animal or single case data. No clinical interaction study was found.27Review
Other supplements1
Other daisy-family (Asteraceae) plant productse.g. chamomile, calendula, echinaceaPeople sensitized to one Asteraceae plant can react to others; LactMed lists chamomile, chrysanthemum, dandelion, marigold and sunflower. In patch testing, arnica and marigold allergies often came with reactions to propolis and fragrance mix.21319Review

Check with what you take

Kept on this device only

Add what you take. We list every interaction our evidence profiles cite between Arnica and your picks, and between your picks.

Most cited:

Add a supplement or medicine you take to check it against Arnica.

Starting from one medicine? The interaction checker rates how serious each pair is, on a curated list of 19 entries for 11 medicines. This cabinet has no severity rating: it lists every interaction row our supplement pages cite.

Not medical advice, and no dosing advice. An empty result means no row we cite names that pair, by name or through a drug class we can link the medicine to, not that a combination is safe. Where our sources name only a group of medicines we cannot match, the cabinet says so. Ask your pharmacist before you combine supplements and medicines.

Who should be careful

8 groups
Daisy-family allergy
People allergic to Asteraceae (Compositae) plants such as chamomile, chrysanthemum, dandelion, marigold or sunflower may react to arnica; about 1% of patch-tested dermatology patients were sensitized to it.31920
Broken skin
LactMed says arnica should not be used on broken skin.3
Anyone, by mouth (non-homeopathic)
Oral botanical arnica (tea, tincture, herb) should be avoided because of its many toxic components, according to LactMed.3
Pregnancy
There are no pregnancy safety data: a 2001 safety assessment found no reproductive or developmental toxicity data for arnica extracts. Swallowed arnica has caused severe gastroenteritis, a fast heart rate and death, and LactMed advises against oral botanical arnica for anyone.283
Breastfeeding
Homeopathic and topical arnica are usually considered safe while breastfeeding, but maternal arnica tea probably caused haemolytic anaemia in one breastfed infant (LactMed).3
Products labelled homeopathic
NCCIH notes that some products labelled homeopathic contain substantial amounts of active ingredients and can cause side effects and drug interactions.13
Liver
LiverTox rates arnica an unlikely cause of liver injury (likelihood score E): no liver injury has been reported with topical or homeopathic use. It notes that FDA classes arnica as an unsafe herb by mouth.29
Blood thinners and surgery
A pharmacy review lists arnica flower among herbs that may add to warfarin's effect or raise bleeding risk; the data are mostly from lab, animal or case reports.27
Talk to your pharmacist or clinician before starting a supplement, especially if you take prescription medicines.

Homeopathic arnica and herbal arnica are not the same product

4 notes

The same name covers a measurable plant extract and a remedy diluted far beyond it.

Herbal arnica
Gels and ointments are made from flower tinctures or extracts and contain the plant's sesquiterpene lactones, which explains the allergy risk; the hand osteoarthritis gel held 50 g of tincture per 100 g.52021
Homeopathic arnica
Pills such as 30x are diluted 1:10^30. A 1998 systematic review concluded the claim that homeopathic arnica works beyond placebo is not supported by rigorous trials; a 2021 meta-analysis found a small effect against placebo that did not reach significance (p = 0.059).141112
How they are regulated
In the US, homeopathic products are regulated as drugs under the Federal Food, Drug, and Cosmetic Act; the FTC said in 2016 that their efficacy claims need the same scientific evidence as other health claims.13
Arnica in food
US regulations list arnica flowers among natural flavouring substances permitted in alcoholic beverages only.2

How to read the label

What to check on the Supplement Facts panel.

How to read the label

3 checks
Herbal or homeopathic?

Look for a dilution such as 6C, 30C or 30x, which marks a homeopathic product, or a percentage or tincture amount, which marks an herbal one. The hand osteoarthritis evidence is for the herbal gel.145

Strength

Trials used a gel with 50 g of tincture per 100 g, and 10% to 20% ointments for bruises.58

Where not to use it

Herbal arnica products are for intact skin; they are not for broken skin or for swallowing.3

Frequently asked questions

Short answers to common questions; the numbers link to the sources below.

Common questions

8 answers
Does arnica gel work for arthritis pain?

For hand osteoarthritis, one 204-person trial found an arnica gel worked as well as 5% ibuprofen gel over 21 days, and Cochrane rated this moderate evidence (grade B). It has not been tested this way in knee or hip arthritis in the sources here.54

Does arnica make bruises fade faster?

The best trial says no: 10% arnica ointment did not reduce bruising after eyelid surgery in 136 patients, and a 2025 systematic review of eyelid-surgery trials found no significant benefit from arnica. An arnica gel did not change laser bruises; one small study of a 20% ointment under occlusion found faster fading than petrolatum.826910

Does arnica reduce muscle soreness?

Results conflict. Topical arnica increased leg pain at 24 hours in one trial and eased tenderness at 72 hours in another; homeopathic arnica 30x did not help 400 runners.6715

Does homeopathic arnica work after surgery?

The evidence is weak and mixed. A 2021 meta-analysis found a small effect against placebo that did not reach significance; a 2020 review saw a possible effect on bruising after rhinoplasty and face-lifts, and trials after knee, hand and eyelid surgery mostly showed no or partial effects.12241417188

Can you take arnica by mouth?

Not as an herb. NIH's LactMed says oral botanical arnica should be avoided because of its toxic components, and LiverTox notes FDA classes arnica as an unsafe herb by mouth. Homeopathic arnica pills are highly diluted and are a different product.32914

Is arnica FDA-approved?

No arnica product in the sources here is FDA-approved for a condition. Homeopathic products are regulated as drugs, and NCCIH notes FDA has warned that some homeopathic products are not evaluated by FDA for safety and effectiveness. Arnica flowers are allowed as a flavouring only in alcoholic beverages.132

Is arnica safe to use before surgery?

A 2000 pharmacy review lists arnica flower among herbs that may raise bleeding risk or add to warfarin's effect, though that rests mostly on lab, animal and case data. Herbal arnica is meant for intact skin only; LactMed says it should not be used on broken skin.273

What are the side effects of arnica?

On the skin, the main risk is allergy: its sesquiterpene lactones, such as helenalin, are strong sensitizers, and about 1.1% of dermatology patients reacted on patch testing. LiverTox rates arnica an unlikely cause of liver injury (score E). Swallowed as an herb, it can cause stomach upset, vomiting and worse.19202928

Sources

29 sources: trial abstracts, NIH fact sheets and reference databases. Numbers in the text link here.

Sources cited on this page

29 sources
  1. 1PubChem compound summary: Helenalin (CID 23205)Database National Library of Medicine, 2026 · pubchem.ncbi.nlm.nih.gov
  2. 221 CFR 172.510 Natural flavoring substances and natural substances used in conjunction with flavors (arnica flowers: in alcoholic beverages only)Guideline Electronic Code of Federal Regulations, 2026 · ecfr.gov
  3. 3Arnica. Drugs and Lactation Database (LactMed).Database National Institute of Child Health and Human Development, 2024 · PMID 30000888
  4. 4Topical herbal therapies for treating osteoarthritis.Systematic review Cochrane Database Syst Rev, 2013 · PMID 23728701
  5. 5Choosing between NSAID and arnica for topical treatment of hand osteoarthritis in a randomised, double-blind study.RCT Rheumatol Int, 2007 · PMID 17318618
  6. 6The effect of topical arnica on muscle pain.RCT Ann Pharmacother, 2010 · PMID 20807867
  7. 7The effects of topical Arnica on performance, pain and muscle damage after intense eccentric exercise.RCT Eur J Sport Sci, 2014 · PMID 23947690
  8. 8Arnica Ointment 10% Does Not Improve Upper Blepharoplasty Outcome: A Randomized, Placebo-Controlled Trial.RCT Plast Reconstr Surg, 2016 · PMID 27348641
  9. 9Effects of topical arnica gel on post-laser treatment bruises.RCT Dermatol Surg, 2002 · PMID 12174058
  10. 10Accelerated resolution of laser-induced bruising with topical 20% arnica: a rater-blinded randomized controlled trial.RCT Br J Dermatol, 2010 · PMID 20412090
  11. 11Efficacy of homeopathic arnica: a systematic review of placebo-controlled clinical trials.Systematic review Arch Surg, 1998 · PMID 9820349
  12. 12Is Homeopathic Arnica Effective for Postoperative Recovery? A Meta-analysis of Placebo-Controlled and Active Comparator Trials.Meta-analysis Front Surg, 2021 · PMID 34977136
  13. 13Homeopathy: What You Need To KnowFact sheet National Center for Complementary and Integrative Health, 2026 · nccih.nih.gov
  14. 14Homeopathic arnica therapy in patients receiving knee surgery: results of three randomised double-blind trials.RCT Complement Ther Med, 2006 · PMID 17105693
  15. 15Homeopathic Arnica 30x is ineffective for muscle soreness after long-distance running: a randomized, double-blind, placebo-controlled trial.RCT Clin J Pain, 1998 · PMID 9758072
  16. 16Effect of Arnica D30 in marathon runners. Pooled results from two double-blind placebo controlled studies.Meta-analysis Homeopathy, 2003 · PMID 14587684
  17. 17Homeopathic arnica for prevention of pain and bruising: randomized placebo-controlled trial in hand surgery.RCT J R Soc Med, 2003 · PMID 12562974
  18. 18Effect of homeopathic Arnica montana on bruising in face-lifts: results of a randomized, double-blind, placebo-controlled clinical trial.RCT Arch Facial Plast Surg, 2006 · PMID 16415448
  19. 19The seamy side of natural medicines: contact sensitization to arnica (Arnica montana L.) and marigold (Calendula officinalis L.).Observational Contact Dermatitis, 2001 · PMID 11722485
  20. 20[Arnica allergy].Review Hautarzt, 1980 · PMID 6993423
  21. 21Contact sensitization from Compositae-containing herbal remedies and cosmetics.Review Contact Dermatitis, 2002 · PMID 12492516
  22. 22Perioperative Arnica montana for Reduction of Ecchymosis in Rhinoplasty Surgery.RCT Ann Plast Surg, 2016 · PMID 25954844
  23. 23Use of Arnica to relieve pain after carpal-tunnel release surgery.RCT Altern Ther Health Med, 2002 · PMID 11892685
  24. 24Perioperative Homeopathic Arnica and Bromelain: Current Results and Future Directions.Systematic review Ann Plast Surg, 2020 · PMID 31800557
  25. 25Can Topical Agents (Arnica and Mucopolysaccharide Polysulfate) Reduce Postoperative Pain, Edema and Trismus Following Mandibular Third Molar Surgery?RCT J Oral Maxillofac Surg, 2024 · PMID 37913818
  26. 26Interventions for reducing bleeding and swelling in eyelid and periocular surgeries: a systematic review of randomized controlled trials.Systematic review Orbit, 2025 · PMID 41264874
  27. 27Potential interactions between alternative therapies and warfarin.Review Am J Health Syst Pharm, 2000 · PMID 10902065
  28. 28Final report on the safety assessment of Arnica montana extract and Arnica montana.Review Int J Toxicol, 2001 · PMID 11558636
  29. 29Arnica MontanaDatabase LiverTox (NCBI Bookshelf), 2023 · ncbi.nlm.nih.gov

What changed

Every dated change to this page: what changed, who made it and why.

Change log

3 entries
Dated changes to this page
DateChangeWho and why
evidence, safety, interactions, FAQ, questionsAdded a graded row for topical arnica after wisdom tooth surgery (2024 trial, 60 patients, no placebo) with its time-to-effect, and the 2025 systematic review of eyelid-surgery trials (no benefit from arnica) to the bruising answer. Added LiverTox (likelihood score E), a pregnancy note (no reproductive toxicity data; oral arnica unsafe), and a warfarin and bleeding caution from a 2000 pharmacy review. Cut the FAQ from 11 to 8 (side effects and before-surgery questions added; open-cut, breastfeeding and interactions answers now covered by the safety section and page questions) and added bones-and-joints and hair-and-skin goal-hub links. PubMed search to October 2026: the 2021 homeopathic meta-analysis does not report a pooled n, so it stays in the FAQ and key facts rather than as a row; a 2026 ten-person homeopathic crossover after tooth extraction was too small for a row.Writer: Kymata Health EditorialTrigger: A–Z audit against docs/supplements/AUDIT-STANDARD.md
allNew page. Every PMID checked with NCBI E-utilities (esummary title, year and journal) and its abstract read with efetch, including the LactMed record; NCCIH's homeopathy page, 21 CFR 172.510 on eCFR and PubChem read on the date shown. Herbal and homeopathic arnica rows are kept apart in the forms table; the 20% ointment bruising trial is cited but not graded because its abstract gives no participant count.Writer: Kymata Health EditorialTrigger: new page
formsThe forms table's tolerance row is labelled "Tolerance" instead of "GI tolerance": it covers gels and creams on the skin as well as pills and tea. No evidence row or grade changed.Writer: Kymata Health EditorialTrigger: adversarial review

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