Cognitive & Nootropic

N-Acetyl Semax Amidate

NASA · NA-Semax Amidate · Ac-Semax-NH2 · N-acetyl Semax amide

N-terminal acetylated, C-terminal amidated Semax. The caps are the same stability trick as N-acetyl Selank amidate. Flagship nasal SKU in the research-chem Semax family. Human PK for this analog is not published - dosing and half-life claims are inferred from parent Semax (ACTH 4–10 analog) plus analog chemistry.

Not FDA-approved - research chemical

Quick answer

What it is: N-terminal acetylated, C-terminal amidated Semax.

Typical research dose: 250-750 mcg/day (intranasal)

Reconstitution calculator ↓

Research summary, not medical advice.

Reviewed by Kymata Health Editorial Team

·Last updated: August 2026·Evidence: Low

Typical research dose

250-750 mcg/day (intranasal)

Frequency

1-2× daily (intranasal)

Half-life

Not published for this analog

Common vials

5 mg / 10 mg

CAS

N/A (modified research peptide)

Molecular weight

~1 kDa class (heptapeptide analog)

Use-case scores

0–10 against the evidence we have, not a gym ranking. Hidden domains do not apply here.

Cognition3/10
Parent Semax literature only. Analog PK is unpublished. Mechanism/community after haircut.

Compound card

Sequence: N-acetyl Semax amide
Class: Stabilized Semax analog (no independent human PK)
Formula: N-acetyl Semax amide
Status: Not FDA-approved · research use

Dose it

5 mg + 2.5 mL BAC water → 2 mg/mL · 250 mcg ≈ 13 units (U-100)

Open in calculator

How it works

NASA is Semax with an N-acetyl cap and a C-terminal amide - the same stability edits used on N-acetyl Selank amidate. Parent Semax is an ACTH 4–10 analog with Russian clinical literature (BDNF/NGF, stroke/cognitive use).

This analog does not have its own human PK paper. Half-life and “stronger/longer” claims are chemistry inference plus vendor copy. Dose ranges below are community nasal SKUs, not a label.

Source: Parent compound: Semax. Analog: no dedicated human PK paper.

Research Use Cases

✓Cognitive / nootropic research: Low

Dosing

Phase	Dose	Frequency	Notes
Intranasal (vendor range)	250–750 mcg/day	1–2× daily	Inherited from Semax practice. No analog-specific trial.

Administration

Route / form

Intranasal (typical SKU) or SC

Timing

Morning or split. No food requirement.

Empty stomach?

No - Food timing is not critical.

N-Acetyl Semax Amidate: Nasal spray / drops vs Research vial SubQ

Nasal spray / drops

Bioavailability

Minutes-class systemic t½ is why the spray exists. Intranasal is a CNS-delivery argument, not a published US F% table for this SKU. Do not print “~100% CNS delivery” as if it were an FDA bioavailability number.

Dose note

Reconstitute the lyophilized cake, then dose the nose. Community ranges sit in the low-hundreds of mcg per day, split 1–3×. That is research-chem / CIS practice, not a US label. Do not run a BPC-style daily SubQ chart on a nasal insert.

Advantages

Matches how the Russian product and most US research SKUs are actually used.
Short plasma t½ is the reason people do not treat this like a depot GH peptide.
NASA is acetyl + amide on Semax. Not N-acetyl Selank amidate. Parent papers stay on Semax.

Considerations

Sold as a nasal research SKU. Not a US NDA. This analog inherits papers from Semax. It does not have its own human PK package.
Nasal irritation is the usual complaint. Volume and osmolarity of a reconstituted cake are not a pharmacy spray.
Recon math is for making a solution. It is not a BAC SubQ lifestyle protocol.

Research vial SubQ

Bioavailability

Same cake, different hole. SubQ is community use of a nasal peptide. There is no head-to-head human PK that makes the shot “stronger.” Minutes-class parent t½ still applies.

Dose note

If the bottle is lyophilized and you inject it, BAC-reconstitute and do the unit math. Community mcg numbers are borrowed from nasal practice. Food does not change the shot. This is not a second official SKU.

Advantages

Vial math is checkable when the COA matches the sequence.
Useful only if you knowingly bought a cake and chose SubQ. It does not create a US injectable drug.

Considerations

Not the Russian labeled route. Do not invent a clinic IM ampoule because a vendor sold powder.
Systemic exposure is not a published reason to skip the nose.
NASA is acetyl + amide on Semax. Not N-acetyl Selank amidate. Parent papers stay on Semax.

Recommendation: N-Acetyl Semax Amidate: nasal is the honest default. SubQ is the same research cake used as an injection, not a second approved product. Sold as a nasal research SKU. Not a US NDA. This analog inherits papers from Semax. It does not have its own human PK package. Do not flatten a spray insert into a BPC reconstitution calendar.

Timeline

Minutes–hours

Parent Semax is fast; analog duration is unmeasured in humans.

Who it is for

Cognitive / nootropic research

Low

High search, thin analog data. Prefer parent Semax papers over NASA marketing.

Reconstitution

Vial

5 mg

Diluent

2.5 mL

Concentration

2 mg/mL

Per Unit (100u syringe)

20 mcg

Dose of 250 mcg = 12.5 units on a 100-unit insulin syringe

Safety & Considerations

Research analog. Nasal irritation possible. Not a substitute for diagnosed stroke or ADHD care. Do not confuse with N-acetyl Selank amidate (different peptide; NASA is Semax).

Regulatory & Legal Status

FDA Status (US)

Research Only

Analog of Semax (Russian ACTH 4–10 drug). This amidated form has no FDA/EMA approval

WADA Status (2026)

Not Listed

Not currently on the WADA 2026 Prohibited List. Policies may change - verify before competition.

Classification

Research Chemical

US Compounding: Not eligible / not available

⚠️ This information is for educational purposes only and may not reflect the most current regulatory updates. Always verify with official FDA, WADA, and jurisdiction-specific sources before use.

Limits of current evidence

No analog-specific human PK paper on this leaf.
Half-life claims are chemistry plus vendor copy.

Verdict

NASA is a stability edit of Semax, not a second Russian stroke program. Read Semax. Do not recon a nasal spray like BPC.

Interactions & Contraindications

Research analog. Nasal irritation possible. Not a substitute for diagnosed stroke or ADHD care. Do not confuse with N-acetyl Selank amidate (different peptide; NASA is Semax).

N-Acetyl Semax Amidate vs. Semax

Canonical comparison: N-Acetyl Semax Amidate vs Semax

Attribute	N-Acetyl Semax Amidate	Semax
Structure	N-acetyl + C-amide Semax (NASA)	Parent ACTH 4–10 heptapeptide
Human PK	Not published for this analog	Russian clinical literature exists
Typical SKU	Nasal research spray	Nasal (including Russian drug product)
Evidence	Low - chemistry inference	Parent papers

Verdict: NASA is a stability analog. Semax is the molecule with papers. Do not treat vendor “longer/stronger” copy as PK.

Frequently Asked Questions

Nasal or injection?▼

NASA is a nasal research analog of Semax. SubQ is optional community use of the cake, not a second trial program. Do not recon a finished pharmacy spray like BPC. Not N-acetyl Selank amidate.

Is NASA the Selank analog?▼

No. NASA is N-Acetyl Semax Amidate. N-Acetyl Selank Amidate is the Selank twin. We keep them as separate library IDs.

Is this more studied than Semax?▼

The opposite. Semax has the papers. NASA is a stability analog with almost no dedicated clinical literature.

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