Brand comparison · NAD+ precursors

NMN, NMNH or NR? ProHealth vs Momentous vs Onnit, compared per gram

NMN, NMNH and NR are all sold to raise NAD+, but their evidence and prices differ a lot. We lined up eight products from three brands and worked out what you pay per gram of the active ingredient.

By Kymata Health Editorial Team · Medical review pending · Prices and labels checked on each brand's own site

Quick answer

  • Evidence first: NMN has randomized trials showing higher blood NAD+ at 250–900 mg/day (grade B). NR raises NAD+ too (grade C for outcomes). NMNH has cell and animal data only (grade D).
  • Cheapest NMN per gram: ProHealth Essentials NMN 1000 at about $1.33 per gram.
  • Combination picks: Momentous Longevity pairs 500 mg Niagen NR with NAC, betaine and PQQ (NSF certified); Onnit NMN + Creatine adds 5 g creatine to 500 mg NMN.
  • Effects on how you feel or perform are still modest and mixed; buy for the NAD+ evidence, not the marketing.

Side by side

One-time price per serving (subscription in brackets), checked Oct 8, 2026. Evidence grade A strong · B moderate · C limited · D preliminary.
ProductLabel per servingEvidencePer servingPer gram of NAD+ precursor
ProHealth Longevity Essentials NMN 1000 (Nexergy)NMN (Nexergy)Nexergy nicotinamide mononucleotide (NMN) 1,000 mgB$1.33($1.20)$1.33
ProHealth Longevity NMN Pro 1000 (Uthever)NMN (Uthever)Uthever β-nicotinamide mononucleotide (NMN) 1,000 mgB$2.17($1.95)$2.17
ProHealth Longevity NMN Pro 500 (Uthever)NMN (Uthever)Uthever β-nicotinamide mononucleotide (NMN) 500 mgB$1.43($1.29)$2.86
Onnit NMN + Creatine (30 ct)NMN + 5 g creatineCreatine monohydrate 5 g; NMN 500 mgB$1.67($1.42)$3.34
ProHealth Longevity Nicotinamide Riboside Pro 300 + TMGNR (hydrogen malate) + TMGNicotinamide riboside (as NR hydrogen malate) 300 mg; TMG 100 mgC$0.83($0.58)$2.77
Momentous LongevityNiagen NR + NAC, betaine, PQQ; NSFNiagen NR 500 mg, NAC 600 mg, betaine 600 mg, PQQ 20 mg, vitamin C 200 mg, niacinamide 28 mg, folate 600 mcg, B12 6 mcgC$3.67($2.75)$7.34
ProHealth Longevity Essentials NMNH 500 (Nexergy+)NMNH (Nexergy+)Nexergy+ NMNH 500 mgD$2.20($1.98)$4.40
ProHealth Longevity Pure NMNH 250 (UthPeak)NMNH (UthPeak)UthPeak NMNH (dihydronicotinamide mononucleotide) 250 mgD$1.60($1.44)$6.40

Our picks

  1. Best value NMN

    ProHealth Longevity Essentials NMN 1000 (Nexergy)

    Lowest cost per gram of NMN, with a product CoA.

    $1.33/serving · grade B

    View at ProHealth LongevityBrand link

  2. Best branded NMN

    ProHealth Longevity NMN Pro 1000 (Uthever)

    Uthever NMN at the top of the studied dose range.

    $2.17/serving · grade B

    View at ProHealth LongevityBrand link

  3. Best NSF-certified option

    Momentous Longevity

    Niagen NR plus methyl-donor support, NSF Certified for Sport.

    $3.67/serving · grade C

    View at MomentousBrand link

What the human research shows

  • NMN: in a 60-day randomized trial of 80 healthy middle-aged adults, 300, 600 and 900 mg/day raised blood NAD+ dose-dependently, highest at 600 and 900 mg (PMID 36482258). In older men, 250 mg/day was well tolerated and raised NAD+ metabolites (PMID 35927255).
  • NR: 1,000 mg/day (500 mg twice daily) raised blood NAD+ in healthy middle-aged and older adults and was well tolerated (PMID 29599478). Functional benefits have not been clearly shown.
  • NMNH: a 2021 cell study found it raised NAD+ more strongly than NMN (PMID 33793246). We found no peer-reviewed human trial as of Oct 8, 2026.

How to choose

  • Want the most evidence per dollar: NMN at 500–1,000 mg/day; the ProHealth Essentials line is the cheapest per gram here.
  • Want a third-party sport certification: Momentous Longevity is NSF Certified for Sport (NR, not NMN).
  • Already taking creatine: Onnit NMN + Creatine combines both in one packet.
  • Curious about NMNH: think of it as an experiment until human data are published.

Safety notes

  • NMN and NR were well tolerated in trials lasting up to a few months; long-term safety data are limited.
  • Not for pregnancy or breastfeeding (no data). Check with your clinician if you take prescription medicines.

FAQ

Is NMN or NR better?

Both raise blood NAD+ in randomized trials. NMN has more recent dose-response data (250–900 mg/day); NR has well-known safety data at 1,000 mg/day. Neither has clearly shown functional benefits yet.

Is NMNH better than NMN?

In cells and mice NMNH raises NAD+ more strongly, but there is no peer-reviewed human trial yet. NMN is the evidence-first choice today.

How much NMN should I take?

Trials used 250–900 mg a day, with the largest NAD+ rise at 600–900 mg. Talk to your clinician before starting if you take prescription medicines.

Related

NMN and NAD+ longevity stack →How we would build a NAD+ routine.ProHealth Longevity review →All 14 ProHealth products we checked.Momentous review →Including the Longevity formula.Onnit review →Including NMN + Creatine.

Sources

Product facts come from each brand's own product pages, read Oct 8, 2026; see each brand review for page-level sources.

  1. Yi L et al. NMN supplementation in healthy middle-aged adults: randomized, dose-dependent trial. GeroScience 2023. · PMID 36482258
  2. Igarashi M et al. Chronic NMN supplementation in healthy older men. NPJ Aging 2022. · PMID 35927255
  3. Martens CR et al. Chronic nicotinamide riboside supplementation in middle-aged and older adults. Nat Commun 2018. · PMID 29599478
  4. Liu Y et al. Reduced nicotinamide mononucleotide (NMNH) potently enhances NAD+ (cell study). J Proteome Res 2021. · PMID 33793246