2 registrations that name pentosan Polysulfate as a study arm and are recruiting or about to, as ClinicalTrials.gov listed them on Oct 20, 2026. Read each listing for its full criteria and current status.
Kymata never assesses eligibility. Each listing names its own criteria; only its study team can say whether someone can join. Trial doses are given under the trial's monitoring and are not a schedule for anyone outside it.
Filter 2 registrations
Status
Phase
All 2 registrations
RecruitingNCT07184827
Evaluate the Efficacy and Safety of U101 Oral Capsules in the Prevention of Uncomplicated rUTIs in Women
Phase 3
TCM Biotech International Corp.
About 348 people
Started Oct 14, 2020
In plain words A Phase 3 study of pentosan Polysulfate in female participants 20 to 75, run by TCM Biotech International Corp.. It plans to enroll about 348 people at 18 sites, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists female participants 20 to 75. Conditions: Recurrent Urinary Tract Infections in Women.
Provide a signed informed consent form.
Non-pregnant, non-nursing females ≥ 20 and < 76 years old.
Having a history of ≥ 2 UTI events during the preceding 6 months or ≥ 3 UTI events during the preceding 12 months (including any UTI event that occurs on the date of ICF signing).
The last urine culture (including those conducted for suspected UTI event or retest) before the randomization has to be negative.
1 more inclusion criterion and the exclusion criteria are on the listing.
What it tests, as registered
U101; Placebo
Registered summary
The goal of this clinical trial is to learn if drug U101 works to prevent recurrent urinary tract infection (rUTI) in women (≥ 20 and \< 76 years old) with a medical history. It will also investigate the safety and the impact on the Quality of Life improvement of drug U101. The full summary is on the listing.
Where, as registered
No US site; Taiwan (18).
RecruitingNCT05245591
Radiation Cystitis Treated With Pentosan Polysulfate Sodium Trial
Phase 2 and 3
National Taiwan University Hospital
About 72 people
Started Apr 29, 2022
In plain words A Phase 2 and 3 study of pentosan Polysulfate in people 20 and older, run by National Taiwan University Hospital. It plans to enroll about 72 people at 1 site, none in the US.
Who it lists and where
Who the trial lists, as registered
Lists people 20 and older. Conditions: Radiation Cystitis.
Capable of giving signed informed consent, which includes compliance with the requirements and restrictions listed in the informed consent form and in the study protocol.
Patients must be ≥20 years of age
Patients must have received definitive radiation therapy for cancer in pelvic area.
Time from the end of radiation therapy to radiation cystitis must be longer than 6 months.
1 more inclusion criterion and the exclusion criteria are on the listing.
The purpose of this study is to evaluate the efficacy and safety of pentosan polysulfate sodium versus placebo and in patients with radiation cystitis who have received radiation therapy in pelvic region.
Where, as registered
No US site; Taiwan (1).
ClinicalTrials.gov lists 5 open registrations for this search, including ones where pentosan Polysulfate is not a study arm or that are past the 2 we keep. Search them on ClinicalTrials.gov (opens in new tab).