Yohimbine and body weight & fat

What 3 graded rows on yohimbine agree on for body weight & fat, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Yohimbine page, with its PubMed record.

Your question

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Yohimbine and body weight & fat

3 rows · 73 people

Mostly an improvement: 2 of 3 rows, and most of the people. 1 found no difference.

No difference
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside.
  • Grade D× 3
Rows
3
Trials
3
People
73

Where they differ

From the rows
How longWho was studied

The best-graded row, grade D, is a randomized trial of 33 people (1991) and found no difference.

The row that found no difference ran longer (6 months) than the 2 rows that found an improvement (3 weeks).

Only the 2 rows that found an improvement name women and athletes or trained people in their population.

The rows

2 improved · 1 no difference
  1. Grade DBody fat in professional soccer players · Improved

    RCT · n 20 · 2006 · Elite male soccer players in Serbia

    20 mg/day in two doses · 21 days

    Body fat fell from 9.3% to 7.1% with yohimbine; body mass, muscle mass and all performance tests did not change. No side effects were reported.

    Row on the Yohimbine page · PubMed 17214405 (opens PubMed)

  2. Grade DWeight loss on a low-calorie diet in women with obesity · Improved

    RCT · n 20 · 1991 · Female outpatients with obesity (Poland), after a 3-week 1,000 kcal/day run-in diet

    5 mg four times daily (20 mg/day) · 3 weeks (with a 1,000 kcal/day diet)

    Weight loss was 3.55 ± 0.24 kg with yohimbine vs 2.21 ± 0.37 kg with placebo (P < 0.005). Serum glycerol, the lipolysis marker, did not change significantly.

    Row on the Yohimbine page · PubMed 1955308 (opens PubMed)

  3. Grade DBody weight, body fat and fat distribution in men · No difference

    RCT · n 33 · 1991 · Men, mean age 42 (USA); 47 randomised, 33 completed

    High dose, titrated to a peak of 43 mg/day · 6 months

    No effect versus placebo on body weight, BMI, total or HDL cholesterol, body fat, waist-to-hip ratio or CT-measured fat distribution.

    Row on the Yohimbine page · PubMed 1960007 (opens PubMed)

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