Wild Yam and menopause

What 2 graded rows on wild yam agree on for menopause, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Wild Yam page, with its PubMed record.

Your question

Supplement

Wild Yam and menopause

2 rows · 73 people

Split. 1 row found an improvement and 1 found no difference.

No difference
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside.
  • Grade D× 2
Rows
2
Trials
2
People
73

Where they differ

From the rows
Trial sizeHow longWhen published

The best-graded row, grade D, is a randomized trial of 50 people (2011) and found an improvement.

The row that found an improvement was larger: 50 people, against 23 people for the row that found no difference.

The row that found an improvement ran longer (12 months) than the row that found no difference (3 months).

The row that found an improvement is newer (2011) than the row that found no difference (2001).

The rows

1 improved · 1 no difference
  1. Grade DMenopausal symptoms (purple yam, not wild yam) · Improved

    RCT · n 50 · 2011 · Menopausal Taiwanese women at two centres (50 randomised)

    Two sachets a day, each containing 12 mg of extract · 12 months

    Total Greene Climacteric Scale scores fell significantly in the yam group by 12 months (p < 0.01) in a placebo-controlled comparison, mainly in anxiety-type symptoms, insomnia and musculoskeletal pain; no safety problems were reported over 12 months.

    Row on the Wild Yam page · PubMed 20653397 (opens PubMed)

  2. Grade DMenopausal symptoms, lipids and sex hormones · No difference

    Crossover RCT · n 23 · 2001 · Healthy women with troublesome menopausal symptoms (average age 53)

    Applied daily (amount not stated in the abstract) · 3 months per arm

    No difference from placebo cream in hot flushes, night sweats or other symptoms; no change in weight, blood pressure, lipids, glucose, FSH, estradiol, or serum or salivary progesterone. No significant side effects.

    Row on the Wild Yam page · PubMed 11428178 (opens PubMed)

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