White Mulberry Leaf and blood sugar
What 5 graded rows on white mulberry leaf agree on for blood sugar, and where they differ. Counted side by side, never averaged.
Consensus finder Rows from the White Mulberry Leaf page, reviewed Oct 21, 2026 How it decides
What the rows agree on
Each block and row is one graded row from the White Mulberry Leaf page, with its PubMed record.
Your question
White Mulberry Leaf and blood sugar
5 rows · 787 peopleMostly an improvement: 4 of 5 rows, and most of the people. 1 had mixed results.
- BGrade B× 3
- CGrade C× 1
- DGrade D× 1
- Rows
- 5
- Trials
- 5
- At least: a review without a trial count
- People
- 787
- Pooled reviews may count some twice
What the rows share
From the rowsThe best-graded row, grade B, is a crossover trial of 38 people (2021) and found an improvement.
The rows run from 37 to 615 people, published from 2017 to 2024: 1 pooled review and 4 single studies.
The rows
4 improved · 1 mixed- BGrade BPost-meal glucose and insulin after a sucrose drink · Improved
Crossover RCT · n 38 · 2021 · Healthy adults (UK)
250 mg blended into 75 g sucrose · Single dose, 120-minute test
Glucose incremental area was 42% lower and insulin incremental area 40% lower than with sucrose alone; no adverse events were reported.
Row on the White Mulberry Leaf page · PubMed 33858439 (opens PubMed)
- BGrade BPost-meal glucose and insulin after a mixed meal (three doses) · Improved
Crossover RCT · n 37 · 2024 · Healthy adults (UK)
200, 225 or 250 mg before a meal of 150 g white bread with egg mayonnaise · Single doses, 3-hour tests
All three doses lowered the 2-hour glucose incremental area by 30–33% and the insulin incremental area by 31–38% versus placebo.
Row on the White Mulberry Leaf page · PubMed 38892603 (opens PubMed)
- BGrade BPost-meal glucose and insulin after maltodextrin (three extract doses) · Improved
Crossover RCT · n 37 · 2017 · Healthy normoglycaemic adults aged 19–59, BMI 20–30 (UK)
125, 250 or 500 mg (6.25, 12.5 or 25 mg DNJ) with 50 g maltodextrin · Single doses, 120-minute tests
Glucose rise (positive incremental area) was 14% lower with 250 mg and 22% lower with 500 mg than placebo; 125 mg was not significant. Insulin rise fell about 24–25% at the two higher doses. Gastrointestinal symptoms did not differ from placebo.
Row on the White Mulberry Leaf page · PubMed 28225835 (opens PubMed)
- CGrade CFasting glucose, HbA1c and fasting insulin · Improved
Meta-analysis · n 615 · 2023 · Adults in 12 randomized trials, healthy and with raised glucose
Varied by trial · Varied; subgroup of 8 weeks or longer
Fasting glucose fell by 0.47 mmol/L, HbA1c by 2.92 mmol/mol and fasting insulin by 0.58 µIU/mL. Effects were larger in trials of 8 weeks or more and in people with baseline fasting glucose above 6.1 mmol/L.
Row on the White Mulberry Leaf page · PubMed 36644880 (opens PubMed)
- DGrade DMetabolic markers over 12 weeks in type 2 diabetes · Mixed
RCT · n 60 · 2022 · Adults with type 2 diabetes (Iran)
300 mg twice daily · 12 weeks
Insulin and malondialdehyde fell and HDL cholesterol rose versus placebo; other metabolic markers measured did not change.
Row on the White Mulberry Leaf page · PubMed 35623877 (opens PubMed)