Valerian Root and insomnia

What 4 graded rows on valerian root agree on for insomnia, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Valerian Root page, with its PubMed record.

Your question

Supplement
Valerian Root Choose another

Valerian Root and insomnia

4 rows · 1,689 people

Split. 2 rows found an improvement and 2 found no difference.

No difference
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside.
  • Grade C× 3
  • No effect× 1
Rows
4
Trials
19
People
1,689
Pooled reviews may count some twice

Where they differ

From the rows
Trial sizeStudy design

The best-graded row, grade C, is a meta-analysis of 1,093 people (2006) and found an improvement. 1 row is graded No effect, our grade for adequately powered trials that found no effect.

The 2 rows that found an improvement were larger: a median of 583 people, against a median of 262 people for the 2 rows that found no difference.

Only the 2 rows that found an improvement include pooled reviews of several trials (1 of 2); the 2 rows that found no difference are single studies.

The rows

2 improved · 2 no difference
  1. Grade CSelf-rated sleep quality (improved or not) · Improved

    Meta-analysis, 16 studies · n 1,093 · 2006 · Adults in 16 placebo-controlled trials

    Varied across trials · Varied

    Across the 6 trials reporting a yes/no outcome, valerian users were 1.8 times as likely to report improved sleep (95% CI 1.2–2.9), but there was evidence of publication bias and most studies had methodological problems.

    Row on the Valerian Root page · PubMed 17145239 (opens PubMed)

  2. Grade CSleep quality (PSQI) and actigraphy sleep latency · Improved

    RCT · n 72 · 2024 · Indian adults aged 18 to 50 with sleep complaints (mild insomnia symptoms)

    200 mg, 1 hour before bedtime · 8 weeks

    PSQI total score fell more than with placebo on days 14, 28 and 56; wrist actigraphy showed shorter sleep latency and longer sleep time from day 3. No safety concerns were seen.

    Row on the Valerian Root page · PubMed 37899385 (opens PubMed)

  3. Grade CSleep quality (PSQI) during cancer treatment · No difference

    RCT · n 119 · 2011 · People undergoing cancer treatment with sleep problems

    450 mg 1 hour before bedtime · 8 weeks

    No difference from placebo on the primary sleep score (P = 0.70). Exploratory analyses favoured valerian on some fatigue measures.

    Row on the Valerian Root page · PubMed 21399726 (opens PubMed)

  4. No effectMinimally important improvement in sleep quality · No difference

    RCT · n 405 · 2007 · Norwegian adults aged 18–75 with insomnia recruited via a TV program

    600 mg/day of extract (3 tablets nightly, per the PMC full text) · 2 weeks

    29% improved on valerian vs 21% on placebo (P = 0.08), not significant. Slightly more valerian users rated their sleep better on a global question (5.5% difference, P = 0.04). No serious adverse events.

    Row on the Valerian Root page · PubMed 17940604 (opens PubMed)

Educational only. Not medical advice. Some links earn us a commission: kymatahealth.com/affiliate-disclosure.