Uva ursi (bearberry) and bladder infection

What 2 graded rows on uva ursi (bearberry) agree on for bladder infection, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Uva ursi (bearberry) page, with its PubMed record.

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Uva ursi (bearberry) and bladder infection

2 rows · 780 people

Split. 1 row found no difference and 1 had mixed results.

No difference or mixed
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.
  • Grade B× 1
  • No effect× 1
Rows
2
Trials
2
People
780

What the rows share

From the rows

The best-graded row, grade B, is a randomized trial of 398 people (2021) and reported mixed results. 1 row is graded No effect, our grade for adequately powered trials that found no effect.

The rows run from 382 to 398 people, published from 2019 to 2021: 2 single studies.

The rows

1 no difference · 1 mixed
  1. No effectUrinary frequency symptoms and antibiotic use vs placebo · No difference

    RCT · n 382 · 2019 · Women aged 18–70 with suspected lower UTI in UK primary care, all given a delayed antibiotic prescription

    Not stated in the abstract · Not stated in the abstract

    No difference in frequency symptoms on days 2–4 (−0.06, p=0.661) and no significant reduction in antibiotic use (39.9% vs 47.4%, p=0.293); no safety concerns.

    Row on the Uva ursi (bearberry) page · PubMed 30685500 (opens PubMed)

  2. Grade BAntibiotic use and symptom burden in uncomplicated UTI vs fosfomycin · Mixed

    RCT · n 398 · 2021 · Adult women with suspected uncomplicated urinary tract infection in 42 German family practices

    2 tablets three times daily (630 mg arbutin/day) · 5 days

    Antibiotic courses were 63.6% lower than with fosfomycin, but total symptom burden was 136.5% of the fosfomycin group (failing non-inferiority), and 8 women developed pyelonephritis versus 2 (p=0.067).

    Row on the Uva ursi (bearberry) page · PubMed 34111592 (opens PubMed)

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