Trigonelline and blood sugar

What 2 graded rows on trigonelline agree on for blood sugar, and where they differ. Counted side by side, never averaged.

Consensus finder Rows from the Trigonelline page, reviewed Oct 21, 2026 How it decides

What the rows agree on

Each block and row is one graded row from the Trigonelline page, with its PubMed record.

Supplement

Trigonelline Choose another

2 rows · 30 people

Split. 1 row found no difference and 1 had mixed results.

No difference or mixed

Improved

Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.

From the rows

The best-graded row, grade D, is a crossover trial of 15 people (2011) and found no difference.

The rows run from 15 people, published from 2009 to 2011: 2 single studies.

1 no difference · 1 mixed

Grade DGLP-1 and GIP responses · No difference
Crossover RCT · n 15 · 2011 · Overweight men (same trial)
500 mg single dose · Single dose
No change in GLP-1 or GIP secretion versus placebo.
Row on the Trigonelline page · PubMed 21299855 (opens PubMed)
Grade DGlucose and insulin during an oral glucose tolerance test · Mixed
Crossover RCT · n 15 · 2009 · Overweight men
500 mg single dose · Single dose
Glucose (−0.5 mmol/L) and insulin (−117 pmol/L) were lower 15 minutes into the test than with placebo; area under the curve over 2 hours did not differ.
Row on the Trigonelline page · PubMed 19324944 (opens PubMed)