Stinging Nettle and prostate

What 3 graded rows on stinging nettle agree on for prostate, and where they differ. Counted side by side, never averaged.

Consensus finder Rows from the Stinging Nettle page, reviewed Oct 21, 2026 How it decides

What the rows agree on

Each block and row is one graded row from the Stinging Nettle page, with its PubMed record.

Supplement

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3 rows · 563 people

They agree: all 3 rows found an improvement.

No difference

Improved

Each block is one evidence row, sized by how many people it enrolled, with its grade inside.

From the rows

The best-graded row, grade C, is a randomized trial of 257 people (2005) and found an improvement.

The rows run from 60 to 257 people, published from 2004 to 2020: 3 single studies.

3 improved

Grade CProstate urinary symptoms with a saw palmetto and nettle root combination · Improved
RCT · n 257 · 2005 · Older men with lower urinary tract symptoms from benign prostatic hyperplasia
2 capsules a day · 24 weeks double-blind, then 24 weeks open-label
IPSS fell 6 points with the combination versus 4 with placebo (p = 0.003, one-tailed); tolerability was similar to placebo.
Row on the Stinging Nettle page · PubMed 15928959 (opens PubMed)
Grade CProstate urinary symptoms (IPSS) over 12 months · Improved
RCT · n 246 · 2004 · Men with benign prostatic syndrome
459 mg/day of dry extract · 12 months
IPSS fell from 18.7 to 13.0 with nettle root versus 18.5 to 13.8 with placebo (p = 0.023). Peak urine flow and leftover urine changed similarly in both groups. Fewer adverse events and urinary infections on nettle root.
Row on the Stinging Nettle page · PubMed 15045190 (opens PubMed)
Grade DProstate urinary symptoms (IPSS) over 12 weeks · Improved
RCT · n 60 · 2020 · Men with benign prostatic hyperplasia
450 mg/day · 12 weeks
The authors report an intermediate effect on IPSS and on superoxide dismutase, a small effect on hs-CRP and an intermediate to large effect on malondialdehyde versus placebo; other measures changed negligibly. No side effects were seen.
Row on the Stinging Nettle page · PubMed 32981268 (opens PubMed)