Saffron and sleep

What 2 graded rows on saffron agree on for sleep, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Saffron page, with its PubMed record.

Your question

Supplement

Saffron and sleep

2 rows · 483 people

They agree: both rows found an improvement.

No difference
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside.
  • Grade C× 1
  • Grade D× 1
Rows
2
Trials
2
At least: a review without a trial count
People
483
Pooled reviews may count some twice

What the rows share

From the rows

The best-graded row, grade C, is a meta-analysis of 431 people (2022) and found an improvement.

The rows run from 52 to 431 people, published from 2022 to 2025: 1 pooled review and 1 single study.

The rows

2 improved
  1. Grade CSleep quality and duration · Improved

    Meta-analysis · n 431 · 2022 · Adults with insomnia complaints in 8 studies

    Not stated in the abstract · Not stated in the abstract

    Sleep quality (SMD 0.89, very low-quality evidence) and sleep duration (SMD 0.57, moderate-quality evidence) improved versus placebo; the reduction in insomnia severity was not significant.

    Row on the Saffron page · PubMed 36141931 (opens PubMed)

  2. Grade DSleep quality in older adults with sleep complaints · Improved

    Pilot RCT · n 52 · 2025 · Adults aged 55–85 with self-reported sleep complaints

    30 mg/day · 4 weeks

    Subjective sleep quality (p = 0.02) and sleep efficiency (p = 0.04) improved versus placebo, and a home EEG sleep tracker recorded a shorter time to fall asleep (p = 0.03).

    Row on the Saffron page · PubMed 40762630 (opens PubMed)

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