Rose Hip and osteoarthritis

What 4 graded rows on rose hip agree on for osteoarthritis, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Rose Hip page, with its PubMed record.

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Rose Hip and osteoarthritis

4 rows · 613 people

Mostly an improvement: 3 of 4 rows, and most of the people. 1 found no difference.

No difference
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside.
  • Grade C× 2
  • Grade D× 2
Rows
4
Trials
6
People
613
Pooled reviews may count some twice

Where they differ

From the rows
Study designWhen published

The best-graded row, grade C, is a meta-analysis of 287 people (2008) and found an improvement.

Only the 3 rows that found an improvement include pooled reviews of several trials (1 of 3); the row that found no difference is a single study.

The row that found no difference is newer (2026) than the 3 rows that found an improvement (2004 to 2008).

The rows

3 improved · 1 no difference
  1. Grade COsteoarthritis pain · Improved

    Meta-analysis, 3 studies · n 287 · 2008 · Adults with osteoarthritis in 3 RCTs

    Varied (5 g/day in the two crossover trials cited here) · Median 3 months

    Pain fell more than with placebo (effect size 0.37), and patients were about twice as likely to respond (OR 2.19), a number needed to treat of 6.

    Row on the Rose Hip page · PubMed 18407528 (opens PubMed)

  2. Grade DOsteoarthritis joint pain and stiffness · Improved

    Crossover RCT · n 112 · 2004 · Adults with osteoarthritis

    5 g/day · 3 months per period

    In the group given placebo first, pain and stiffness improved more on rose hip; in the group given rose hip first, placebo appeared to work as well, which the authors attribute to carryover. In the first 3 months, 66% responded on rose hip versus 36% on placebo; no major side effects.

    Row on the Rose Hip page · PubMed 15330493 (opens PubMed)

  3. Grade DHip and knee osteoarthritis pain, stiffness and rescue-medication use · Improved

    Crossover RCT · n 94 · 2005 · Adults with hip or knee osteoarthritis

    5 g/day · 3 months per period

    WOMAC pain fell versus placebo by 3 weeks and rescue-medication use declined; disability, stiffness and global severity improved by 3 months.

    Row on the Rose Hip page · PubMed 16195164 (opens PubMed)

  4. Grade CHip and knee osteoarthritis pain and function · No difference

    RCT · n 120 · 2026 · Adults with mild to moderate hip or knee osteoarthritis (multicentre trial NCT01459939), 60 per group

    5 g/day for 3 weeks, then 2.5 g/day · 12 weeks

    WOMAC pain and function improved by more than 50% in both groups, with no significant difference between rose hip and placebo. A secondary analysis found larger improvement with a higher dose per kg of body weight in the rose hip group only.

    Row on the Rose Hip page · PubMed 41599942 (opens PubMed)

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