Pterostilbene and healthy aging

What 3 graded rows on pterostilbene agree on for healthy aging, and where they differ. Counted side by side, never averaged.

Consensus finder Rows from the Pterostilbene page, reviewed Oct 21, 2026 How it decides

What the rows agree on

Each block and row is one graded row from the Pterostilbene page, with its PubMed record.

Supplement

Pterostilbene Choose another

3 rows · 192 people

Mostly an improvement: 2 of 3 rows, and most of the people. 1 found no difference.

No difference

Improved

Each block is one evidence row, sized by how many people it enrolled, with its grade inside.

From the rows

Trial sizeWho was studied

The best-graded row, grade D, is a randomized trial of 120 people (2017) and found an improvement.

The 2 rows that found an improvement were larger: a median of 80 people, against 32 people for the row that found no difference.

Only the 2 rows that found an improvement name women and older adults in their population.

2 improved · 1 no difference

Grade DBlood NAD+ in older adults (with nicotinamide riboside) · Improved
RCT · n 120 · 2017 · Healthy adults aged 60–80
Recommended or double dose of the combination · 8 weeks
Blood NAD+ rose about 40% (standard dose) and 90% (double dose) at 4 weeks versus placebo and stayed up.
Row on the Pterostilbene page · PubMed 29184669 (opens PubMed)
Grade DMenopause-transition symptoms (with nicotinamide riboside) · Improved
Open-label trial · n 40 · 2026 · Women over 35: 32 with menopause-transition symptoms and 8 without
250 mg nicotinamide riboside + 50 mg pterostilbene daily · 7 days
In the 32 women with symptoms, bloating, hot flushes and poor sleep fell in frequency and severity from baseline, and the urinary estradiol-to-estrone ratio rose; women without symptoms showed no change.
Row on the Pterostilbene page · PubMed 42211736 (opens PubMed)
Grade DMuscle recovery after injury (with nicotinamide riboside) · No difference
RCT · n 32 · 2022 · Adults aged 55–80 given an electrically induced muscle injury
1,000 mg nicotinamide riboside + 200 mg pterostilbene daily · Started 2 weeks before the injury; biopsies up to 30 days after
NRPT did not change muscle stem-cell recruitment, fiber size or other measures of muscle recovery versus placebo, and was reported safe.
Row on the Pterostilbene page · PubMed 35998039 (opens PubMed)