D-Pinitol and blood sugar
What 5 graded rows on d-pinitol agree on for blood sugar, and where they differ. Counted side by side, never averaged.
Consensus finder Rows from the D-Pinitol page, reviewed Oct 21, 2026 How it decides
What the rows agree on
Each block and row is one graded row from the D-Pinitol page, with its PubMed record.
Your question
D-Pinitol and blood sugar
5 rows · 167 peopleSplit. 3 rows found an improvement, 1 found no difference and 1 had mixed results.
- DGrade D× 5
- Rows
- 5
- Trials
- 5
- People
- 167
Where they differ
From the rowsThe best-graded row, grade D, is a randomized trial of 52 people (2026) and found an improvement.
The 3 rows that found an improvement were larger: a median of 40 people, against 15 people for the row that found no difference.
The 3 rows that found an improvement ran longer (3 months) than the row that found no difference (6 weeks).
Only the row that found no difference names older adults in its population.
The 3 rows that found an improvement are newer (2005 to 2026) than the row that found no difference (2004).
1 row with mixed results is left out of this comparison.
The rows
3 improved · 1 no difference · 1 mixed- DGrade DHbA1c and glucose in prediabetes · Improved
RCT · n 52 · 2026 · Adults with prediabetes (Spain)
6.66 g/day of concentrate in two doses (pinitol content not stated in the abstract) · 90 days
HbA1c and glucose improved versus placebo; insulin, HOMA-IR and glucose and insulin curves after a glucose drink improved only within the carob group. No adverse effects were recorded.
- DGrade DInsulin sensitivity and postprandial glucose · Improved
RCT · n 40 · 2016 · Healthy adults
2.23 g inositols twice daily · 12 weeks
Insulin, HOMA-IR and Apo B fell and LDL particle size rose; mean post-meal glucose was about 14% lower; the sucrose group gained BMI and fasting glucose.
- DGrade DBlood sugar control in type 2 diabetes · Improved
RCT · n 30 · 2005 · Korean adults with type 2 diabetes
600 mg twice daily (1,200 mg/day) · 13 weeks
Fasting glucose, insulin, fructosamine, HbA1c and HOMA-IR fell versus placebo; total and LDL cholesterol and systolic and diastolic blood pressure also fell, and HDL rose.
- DGrade DGlucose tolerance and insulin sensitivity · No difference
RCT · n 15 · 2004 · Non-diabetic older adults (mean age 66)
1,000 mg twice daily (2,000 mg/day) · 6 weeks
Fasting glucose, insulin and C-peptide and the responses to oral and intravenous glucose tests did not change versus placebo, nor did insulin sensitivity or muscle insulin-receptor measures, although urinary pinitol rose 17-fold.
- DGrade DPost-drink glucose and insulin · Mixed
Crossover RCT · n 30 · 2013 · Healthy adults
Single dose of 2.5, 4.0 or 6.0 g · Single day per condition
Only the 6.0 g dose lowered serum glucose and insulin at 45 and 60 minutes; plasma pinitol rose with dose.