Multivitamin (multivitamin/mineral) and memory

What 2 graded rows on multivitamin (multivitamin/mineral) agree on for memory, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Multivitamin (multivitamin/mineral) page, with its PubMed record.

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Multivitamin (multivitamin/mineral) and memory

2 rows · 8,765 people

They agree: both rows found an improvement.

No difference
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside.
  • Grade C× 2
Rows
2
Trials
4
People
8,765
Pooled reviews may count some twice

What the rows share

From the rows

The best-graded row, grade C, is a meta-analysis of 5,203 people (2024) and found an improvement.

The rows run from 3,562 to 5,203 people, published from 2023 to 2024: 1 pooled review and 1 single study.

The rows

2 improved
  1. Grade CGlobal cognition and episodic memory · Improved

    Meta-analysis, 3 studies · n 5,203 · 2024 · US adults aged 60+ in three COSMOS substudies (Clinic, Mind, Web)

    1 tablet/day · 2–3 years

    Global cognition +0.07 SD units (95% CI 0.03–0.11) and episodic memory +0.06 SD units versus placebo; the authors equated the global effect to about 2 years less cognitive aging.

    Row on the Multivitamin (multivitamin/mineral) page · PubMed 38244989 (opens PubMed)

  2. Grade CImmediate word recall (episodic memory) · Improved

    RCT · n 3,562 · 2023 · Older US adults in COSMOS-Web (online testing)

    1 tablet/day · 3 years

    Better immediate word recall than placebo at 1 year (the primary endpoint) and on average over 3 years; no significant effects on secondary outcomes.

    Row on the Multivitamin (multivitamin/mineral) page · PubMed 37244291 (opens PubMed)

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