MicroLactin (hyperimmune milk protein) and joint discomfort

What 2 graded rows on microlactin (hyperimmune milk protein) agree on for joint discomfort, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the MicroLactin (hyperimmune milk protein) page, with its PubMed record.

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MicroLactin (hyperimmune milk protein) and joint discomfort

2 rows · 89 people

They agree: both rows found an improvement.

No difference
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside.
  • Grade D× 2
Rows
2
Trials
2
People
89

What the rows share

From the rows

The best-graded row, grade D, is a randomized trial of 58 people (2019) and found an improvement.

The rows run from 31 to 58 people, published from 2002 to 2019: 2 single studies.

The rows

2 improved
  1. Grade DKnee discomfort (WOMAC, visual analogue scales) and 6-minute walk distance · Improved

    RCT · n 58 · 2019 · Adults aged about 42–46 with mild to moderate knee pain during activity but no osteoarthritis diagnosis

    4,000 mg/day (2,000 mg twice daily) · 8 weeks

    6-minute walk distance improved 9% vs 2% with placebo (about 110 m difference), and 11 WOMAC items and 5 discomfort scales improved versus placebo. Blood safety markers stayed normal.

    Row on the MicroLactin (hyperimmune milk protein) page · PubMed 30696041 (opens PubMed)

  2. Grade DKnee osteoarthritis symptoms (WOMAC composite from KOOS) · Improved

    RCT · n 31 · 2002 · Adults with osteoarthritis of both knees

    12 oz/day · 6 weeks

    The WOMAC composite improved more than with placebo (moderate effect size 0.56); safety indicators did not change.

    Row on the MicroLactin (hyperimmune milk protein) page · PubMed 11985942 (opens PubMed)

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