Magnesium oxide and constipation

What 2 graded rows on magnesium oxide agree on for constipation, and where they differ. Counted side by side, never averaged.

Consensus finder Rows from the Magnesium oxide page, reviewed Oct 21, 2026 How it decides

What the rows agree on

Each block and row is one graded row from the Magnesium oxide page, with its PubMed record.

Supplement

Magnesium oxide Choose another

2 rows · 124 people

They agree: both rows found an improvement.

No difference

Improved

Each block is one evidence row, sized by how many people it enrolled, with its grade inside.

From the rows

The best-graded row, grade B, is a randomized trial of 90 people (2021) and found an improvement.

The rows run from 34 to 90 people, published from 2019 to 2021: 2 single studies.

2 improved

Grade BOverall improvement in chronic constipation · Improved
RCT · n 90 · 2021 · Adults with chronic idiopathic constipation, 93% women
1.5 g/day · 28 days
68.3% responded on magnesium oxide vs 11.7% on placebo (senna 69.2%). Spontaneous bowel movements and constipation quality of life improved; no severe treatment-related adverse events.
Row on the Magnesium oxide page · PubMed 32969946 (opens PubMed)
Grade BOverall improvement in chronic constipation · Improved
RCT · n 34 · 2019 · Japanese women with mild to moderate chronic constipation
0.5 g three times daily (1.5 g/day) · 28 days
70.6% met the primary endpoint vs 25.0% on placebo; stool form, colonic transit time and quality of life improved. Complete spontaneous bowel movement response did not differ.
Row on the Magnesium oxide page · PubMed 31587548 (opens PubMed)