Magnesium citrate and arterial stiffness

What 2 graded rows on magnesium citrate agree on for arterial stiffness, and where they differ. Counted side by side, never averaged.

Consensus finder Rows from the Magnesium citrate page, reviewed Oct 21, 2026 How it decides

What the rows agree on

Each block and row is one graded row from the Magnesium citrate page, with its PubMed record.

Supplement

Magnesium citrate Choose another

2 rows · 238 people

They agree: both rows found no difference.

No difference

Improved

Each block is one evidence row, sized by how many people it enrolled, with its grade inside.

From the rows

The best-graded row, grade C, is a randomized trial of 164 people (2022) and found no difference.

The rows run from 74 to 164 people, published from 2022 to 2026: 2 single studies.

2 no difference

Grade CArterial stiffness and blood pressure · No difference
RCT · n 164 · 2022 · Adults with overweight or mild obesity, mean age 63 (four arms: citrate, oxide, sulfate, placebo)
450 mg/day magnesium · 24 weeks
Citrate did not change carotid-femoral pulse wave velocity or blood pressure versus placebo. It raised plasma and urinary magnesium, with a larger urinary rise than oxide or sulfate.
Row on the Magnesium citrate page · PubMed 35253448 (opens PubMed)
Grade CCalcification propensity and arterial stiffness in type 2 diabetes · No difference
RCT · n 74 · 2026 · Older adults (median age 72) with type 2 diabetes, arterial calcification in the legs and stiff arteries (Netherlands)
About 350 mg/day magnesium (3 × 117 mg) · 6 months
No improvement in serum calcification propensity (T50). Pulse wave velocity rose slightly versus placebo (0.8 m/s, P = 0.021), but not after adjusting for baseline differences. Urinary magnesium rose but serum magnesium did not.
Row on the Magnesium citrate page · PubMed 41903889 (opens PubMed)