Lycopene and blood vessels

What 2 graded rows on lycopene agree on for blood vessels, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Lycopene page, with its PubMed record.

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Lycopene and blood vessels

2 rows · 254 people

Split. 1 row found an improvement and 1 had mixed results.

Mixed
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.
  • Grade C× 2
Rows
2
Trials
5
People
254
Pooled reviews may count some twice

What the rows share

From the rows

The best-graded row, grade C, is a meta-analysis of 182 people (2026) and found an improvement.

The rows run from 72 to 182 people, published from 2014 to 2026: 1 pooled review and 1 single study.

The rows

1 improved · 1 mixed
  1. Grade CEndothelial function (flow-mediated dilation) · Improved

    Meta-analysis, 4 studies · n 182 · 2026 · Healthy adults in 4 studies of at least 7 days

    Varied; a separate study outside the pooled analysis used 15 mg/day for 8 weeks · At least 7 days

    Flow-mediated dilation rose by 1.36 percentage points (95% CI 0.20 to 2.51); the result lost significance when one study was excluded.

    Row on the Lycopene page · PubMed 42588128 (opens PubMed)

  2. Grade CEndothelial function (forearm blood flow) · Mixed

    RCT · n 72 · 2014 · 36 statin-treated adults with cardiovascular disease and 36 healthy volunteers

    7 mg/day · 2 months

    Endothelium-dependent vasodilation improved 53% versus placebo in heart patients, with no change in healthy volunteers; blood pressure, arterial stiffness, lipids and hsCRP did not change in either group.

    Row on the Lycopene page · PubMed 24911964 (opens PubMed)

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