Lactoferrin and infections

What 2 graded rows on lactoferrin agree on for infections, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Lactoferrin page, with its PubMed record.

Your question

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Lactoferrin and infections

2 rows · 1,339 people

They agree: both rows found an improvement.

No difference
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside.
  • Grade C× 2
Rows
2
Trials
7
People
1,339
Pooled reviews may count some twice

What the rows share

From the rows

The best-graded row, grade C, is a meta-analysis of 1,194 people (2021) and found an improvement.

The rows run from 145 to 1,194 people, published from 2021 to 2023: 1 pooled review and 1 single study.

The rows

2 improved
  1. Grade CRespiratory tract infections · Improved

    Meta-analysis, 6 studies · n 1,194 · 2021 · Participants in 6 randomized trials (9 eligible)

    Varied across trials · Varied across trials

    Odds of a respiratory infection were 43% lower than control (odds ratio 0.57); two trials were at high risk of bias.

    Row on the Lactoferrin page · PubMed 34620326 (opens PubMed)

  2. Grade CRespiratory and whole-body symptom scores in healthy adults · Improved

    RCT · n 145 · 2023 · Healthy adults at a Japanese university

    200 mg/day · 12 weeks

    Total respiratory and systemic symptom scores were lower than with placebo, and plasmacytoid dendritic cell activation markers were higher at week 12; adverse events did not differ.

    Row on the Lactoferrin page · PubMed 37764743 (opens PubMed)

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