Lactium (alpha-s1 casein hydrolysate) and sleep

What 2 graded rows on lactium (alpha-s1 casein hydrolysate) agree on for sleep, and where they differ. Counted side by side, never averaged.

Consensus finder Rows from the Lactium (alpha-s1 casein hydrolysate) page, reviewed Oct 21, 2026 How it decides

What the rows agree on

Each block and row is one graded row from the Lactium (alpha-s1 casein hydrolysate) page, with its PubMed record.

Supplement

Lactium (alpha-s1 casein hydrolysate) Choose another

2 rows · 82 people

Split. 1 row found an improvement and 1 had mixed results.

Mixed

Improved

Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.

From the rows

The best-graded row, grade D, is a crossover trial of 43 people (2019) and reported mixed results.

The rows run from 39 to 43 people, published from 2019 to 2022: 2 single studies.

1 improved · 1 mixed

Grade DSleep quality in poor sleepers (with L-theanine) · Improved
Crossover RCT · n 39 · 2022 · Working adults with poor sleep quality (Malaysia)
Capsules with 150 mg hydrolysate + 50 mg L-theanine each · 4 weeks
PSQI total score, sleep latency, duration and efficiency improved, and total sleep was 45 minutes longer than on placebo; only sleep duration and habitual efficiency held up in both analyses.
Row on the Lactium (alpha-s1 casein hydrolysate) page · PubMed 35277011 (opens PubMed)
Grade DSleep quality in adults with mild-to-moderate sleep disturbance · Mixed
Crossover RCT · n 43 · 2019 · Community adults with poor sleep quality, mean age 49 (Korea)
300 mg/day · 4 weeks per period
Sleep-disturbance scales and daytime functioning improved similarly on Lactium and placebo; sleep diaries (longer sleep, shorter onset, less waking) and actigraphy sleep efficiency favoured Lactium; polysomnography showed no significant difference.
Row on the Lactium (alpha-s1 casein hydrolysate) page · PubMed 31252661 (opens PubMed)