Kanna and cognition

What 2 graded rows on kanna agree on for cognition, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Kanna page, with its PubMed record.

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Kanna and cognition

2 rows · 81 people

Split. 1 row found an improvement and 1 had mixed results.

Mixed
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.
  • Grade D× 2
Rows
2
Trials
2
People
81

What the rows share

From the rows

The best-graded row, grade D, is a randomized trial of 60 people (2020) and reported mixed results.

The rows run from 21 to 60 people, published from 2014 to 2020: 2 single studies.

The rows

1 improved · 1 mixed
  1. Grade DCognitive set flexibility and executive function · Improved

    Crossover RCT · n 21 · 2014 · Cognitively healthy adults (mean age 55, Canada)

    25 mg/day · 3 weeks per arm

    Cognitive set flexibility (p<0.032) and executive function (p<0.022) improved versus placebo; positive changes in mood and sleep were reported. Well tolerated.

    Row on the Kanna page · PubMed 25389443 (opens PubMed)

  2. Grade DReaction performance, alertness and mood · Mixed

    RCT · n 60 · 2020 · Recreationally trained men and women aged 20–35 (Israel)

    25 mg/day · 8 days

    Complex reactive performance under cognitive load improved versus placebo, but alertness, energy, total mood score and simple reaction time did not change.

    Row on the Kanna page · PubMed 32740286 (opens PubMed)

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