IP6 (Inositol Hexaphosphate, Phytate) and uric acid

What 2 graded rows on ip6 (inositol hexaphosphate, phytate) agree on for uric acid, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the IP6 (Inositol Hexaphosphate, Phytate) page, with its PubMed record.

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IP6 (Inositol Hexaphosphate, Phytate) and uric acid

2 rows · 79 people

Split. 1 row found an improvement and 1 had mixed results.

Mixed
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.
  • Grade D× 2
Rows
2
Trials
2
People
79

What the rows share

From the rows

The best-graded row, grade D, is a crossover trial of 48 people (2020) and reported mixed results.

The rows run from 31 to 48 people, published from 2019 to 2020: 2 single studies.

The rows

1 improved · 1 mixed
  1. Grade DFasting serum uric acid in people with high uric acid · Improved

    Crossover RCT · n 31 · 2019 · Japanese adults with asymptomatic hyperuricemia (fasting uric acid above 7.0 but below 9.0 mg/dL)

    600 mg twice daily (1,200 mg/day) · 2 weeks per period, 2-week washout

    Fasting serum uric acid was lower in the IP6 period than the placebo period (p < 0.05); the urinary uric acid to creatinine ratio did not change.

    Row on the IP6 (Inositol Hexaphosphate, Phytate) page · PubMed 31119466 (opens PubMed)

  2. Grade DRise in uric acid after a purine-rich meal · Mixed

    Crossover RCT · n 48 · 2020 · Healthy adults with normal fasting uric acid

    Not stated in the abstract · Single dose with a purine-rich meal; uric acid measured for 360 minutes

    The rise in serum uric acid after the meal (incremental area under the curve) was lower with phytic acid only at p < 0.10, a trend rather than a conventionally significant result.

    Row on the IP6 (Inositol Hexaphosphate, Phytate) page · PubMed 31469027 (opens PubMed)

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