Gamma-Tocopherol and air pollutants

What 2 graded rows on gamma-tocopherol agree on for air pollutants, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Gamma-Tocopherol page, with its PubMed record.

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Gamma-Tocopherol and air pollutants

2 rows · 26 people

Split. 1 row found no difference and 1 had mixed results.

No difference or mixed
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.
  • Grade D× 2
Rows
2
Trials
2
People
26

What the rows share

From the rows

The best-graded row, grade D, is a crossover trial of 15 people (2020) and found no difference.

The rows run from 11 to 15 people, published from 2020 to 2023: 2 single studies.

The rows

1 no difference · 1 mixed
  1. Grade DOzone-induced airway inflammation in asthma · No difference

    Crossover RCT · n 15 · 2020 · Adults with mild intermittent allergic asthma exposed to 0.25 ppm ozone for 3 hours

    About 1,200 mg gamma-tocopherol every 12 hours for 4 doses · 2 days before each exposure

    The short course did not reduce ozone-induced airway inflammation; a transient slowing of large-airway clearance after ozone was seen with placebo but not with gamma-tocopherol.

    Row on the Gamma-Tocopherol page · PubMed 32727225 (opens PubMed)

  2. Grade DWood smoke-induced airway inflammation · Mixed

    Pilot RCT · n 11 · 2023 · Adult volunteers aged 18 to 45 who responded to a screening wood smoke exposure (some with allergies or mild asthma)

    1,253 mg gamma-tocopherol every 12 hours for 4 doses (n = 4) or 1,154 to 1,253 mg once daily for 7 days (n = 7) · 2 or 7 days before exposure

    Gamma-tocopherol did not reduce wood smoke-induced neutrophilic airway inflammation (the primary end point), but it prevented the rise in airway eosinophils.

    Row on the Gamma-Tocopherol page · PubMed 37876758 (opens PubMed)

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