Flower pollen extract and pelvic pain

What 5 graded rows on flower pollen extract agree on for pelvic pain, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Flower pollen extract page, with its PubMed record.

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Flower pollen extract and pelvic pain

5 rows · 794 people

Mostly an improvement: 4 of 5 rows, and most of the people. 1 had mixed results.

Mixed
Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.
  • Grade B× 2
  • Grade C× 3
Rows
5
Trials
8
People
794
Pooled reviews may count some twice

What the rows share

From the rows

The best-graded row, grade B, is a meta-analysis of 384 people (2017) and found an improvement.

The rows run from 60 to 384 people, published from 2006 to 2022: 1 pooled review and 4 single studies.

The rows

4 improved · 1 mixed
  1. Grade BQuality of life in chronic prostatitis (pooled trials) · Improved

    Meta-analysis, 4 studies · n 384 · 2017 · Men with chronic prostatitis/chronic pelvic pain syndrome in 4 randomised trials

    As used in each trial · Varied by trial

    Pollen extract significantly improved quality of life (OR 0.52; 0.34 to 0.81). Six uncontrolled studies (206 men) reported a mean 83.6% response rate. No significant adverse events were reported.

    Row on the Flower pollen extract page · PubMed 28431537 (opens PubMed)

  2. Grade BPelvic pain and quality of life in chronic prostatitis · Improved

    RCT · n 139 · 2009 · Men with inflammatory chronic prostatitis/chronic pelvic pain syndrome (NIH IIIA) attending urology centres

    2 capsules every 8 hours (capsule strength not given in the abstract) · 12 weeks

    Pain (p = 0.0086), quality of life (p = 0.025) and total NIH-CPSI score (p = 0.0126) improved more than with placebo; 70.6% vs 50.0% responded (p = 0.0141). Adverse events were minor.

    Row on the Flower pollen extract page · PubMed 19524353 (opens PubMed)

  3. Grade CChronic prostatitis symptoms vs ibuprofen (pollen extract suppositories) · Improved

    RCT · n 124 · 2022 · Men with chronic prostatitis/chronic pelvic pain syndrome (mean age 34.6)

    1 suppository daily for 10 days (vs ibuprofen 600 mg/day) · 10 days of treatment, follow-up to 6 months

    56 of 63 men (88.8%) on the pollen suppositories had a significant fall in NIH-CPSI total score, compared with 17 of 61 on ibuprofen; quality of life improved more, and adverse events were mild and less frequent than with ibuprofen.

    Row on the Flower pollen extract page · PubMed 33781014 (opens PubMed)

  4. Grade CSymptoms of chronic nonbacterial prostatitis · Improved

    RCT · n 60 · 2006 · Men aged 20 to 55 with chronic nonbacterial prostatitis/chronic pelvic pain syndrome for more than 6 months who had not responded to therapy

    Not stated in the abstract · 6 months

    More men on the pollen extract were rated cured or improved than on placebo; no adverse reactions were found.

    Row on the Flower pollen extract page · PubMed 16413333 (opens PubMed)

  5. Grade CPelvic pain vs tadalafil, added to an alpha-blocker · Mixed

    RCT · n 87 · 2020 · Japanese men with chronic prostatitis/chronic pelvic pain syndrome and urinary symptoms despite alpha-blocker therapy (100 randomised)

    4 capsules per day (vs tadalafil 5 mg/day) · 12 weeks

    Total NIH-CPSI score fell more with cernitin (−6.8 vs −4.6; p = .02), as did the pain score (−4.1 vs −1.5; p < .001), but urinary symptoms improved more with tadalafil.

    Row on the Flower pollen extract page · PubMed 32648985 (opens PubMed)

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