Ferulic acid and skin

What 2 graded rows on ferulic acid agree on for skin, and where they differ. Counted side by side, never averaged.

Consensus finder Rows from the Ferulic acid page, reviewed Oct 21, 2026 How it decides

What the rows agree on

Each block and row is one graded row from the Ferulic acid page, with its PubMed record.

Supplement

Ferulic acid Choose another

2 rows · 76 people

They agree: both rows found an improvement.

No difference

Improved

Each block is one evidence row, sized by how many people it enrolled, with its grade inside.

From the rows

The best-graded row, grade C, is a randomized trial of 60 people (2025) and found an improvement.

The rows run from 16 to 60 people, published from 2023 to 2025: 2 single studies.

2 improved

Grade CRosacea lesions with topical ferulic acid added to doxycycline · Improved
RCT · n 60 · 2025 · Chinese adults with mild-to-moderate papulopustular rosacea
Applied twice daily (with doxycycline 0.1 g/day) · 6 weeks
Lesion and self-assessment scores improved more than with saline; overall response 80.0% vs 63.3%. One person reported tingling and itching; no serious adverse reactions.
Row on the Ferulic acid page · PubMed 39413013 (opens PubMed)
Grade DSkin barrier (water loss and hydration) · Improved
Pilot RCT · n 16 · 2023 · Healthy Japanese men
200 mg/day · 2 weeks
Transepidermal water loss fell from 6.1 to 4.8 g/m2/h and hydration rose from 30.1 to 32.3 units versus baseline; the change in sympathetic nerve activity differed from placebo.
Row on the Ferulic acid page · PubMed 33973806 (opens PubMed)