Elderberry and flu

What 2 graded rows on elderberry agree on for flu, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Elderberry page, with its PubMed record.

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Elderberry and flu

2 rows · 147 people

Split. 1 row found an improvement and 1 found no difference.

No difference
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside.
  • Grade C× 1
  • Grade D× 1
Rows
2
Trials
2
People
147

Where they differ

From the rows
Who was studiedWhen publishedGrade

The best-graded row, grade C, is a randomized trial of 87 people (2020) and found no difference.

Only the row that found no difference names older adults in its population.

The row that found no difference is newer (2020) than the row that found an improvement (2004).

The best grade is C among the row that found no difference, and D among the row that found an improvement.

The rows

1 improved · 1 no difference
  1. Grade DInfluenza symptom duration · Improved

    RCT · n 60 · 2004 · Adults 18–54 with influenza-like symptoms for 48 h or less (Norway, 1999–2000 season)

    15 mL four times a day · 5 days

    Symptoms were relieved on average 4 days earlier, and rescue medication use was lower, than with placebo syrup.

    Row on the Elderberry page · PubMed 15080016 (opens PubMed)

  2. Grade CInfluenza duration and severity (lab-confirmed flu) · No difference

    RCT · n 87 · 2020 · Emergency-room patients aged 5 and older with PCR-confirmed influenza and symptoms under 48 h (US)

    15 mL (5.7 g extract) four times a day over age 12; twice a day ages 5–12 · 5 days

    Days until symptoms were mild or gone did not differ (5.3 vs 4.9 days, p=0.57), nor did days to full resolution (8.6 vs 8.7, p=0.87). A post hoc analysis found elderberry alone did about 2 days worse than placebo alone.

    Row on the Elderberry page · PubMed 32929634 (opens PubMed)

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