Ecdysterone and strength and muscle
What 4 graded rows on ecdysterone agree on for strength and muscle, and where they differ. Counted side by side, never averaged.
Consensus finder Rows from the Ecdysterone page, reviewed Oct 21, 2026 How it decides
What the rows agree on
Each block and row is one graded row from the Ecdysterone page, with its PubMed record.
Your question
Ecdysterone and strength and muscle
4 rows · 160 peopleSplit. 2 rows found an improvement and 2 found no difference.
- DGrade D× 2
- ∅No effect× 2
- Rows
- 4
- Trials
- 4
- People
- 160
Where they differ
From the rowsThe best-graded row, grade D, is a randomized trial of 46 people (2019) and found an improvement. 2 rows are graded No effect, our grade for adequately powered trials that found no effect.
Only the 2 rows that found no difference name athletes or trained people in their population.
The rows
2 improved · 2 no difference- DGrade DMuscle mass and bench press strength during resistance training · Improved
RCT · n 46 · 2019 · Young men in a 10-week strength-training programme (Germany)
12 mg or 48 mg 20E/day · 10 weeks
Participants dosed with ecdysterone gained more muscle mass and more one-repetition bench press strength than comparison participants; liver and kidney markers did not rise.
Row on the Ecdysterone page · PubMed 31123801 (opens PubMed)
- DGrade DMuscle strength with moderate training in adults over 50 · Improved
RCT · n 45 · 2021 · Adults over 50 in a 12-week moderate-intensity training programme (Spain); 23 extract and 22 placebo analysed
2 g/day of extract (4 × 500 mg capsules) · 12 weeks
Strength improved in both groups, but isokinetic and isometric knee-extension gains were larger with the extract; no adverse events were recorded.
Row on the Ecdysterone page · PubMed 34959924 (opens PubMed)
- ∅No effectStrength, body composition and hormones during resistance training · No difference
RCT · n 45 · 2006 · Resistance-trained young men (USA); 45 across four groups (placebo, ecdysterone and two other supplements)
200 mg/day as labelled · 8 weeks
No differences from placebo in fat-free mass, body fat, bench press or leg press strength, sprint power, testosterone or cortisol.
Row on the Ecdysterone page · PubMed 18500969 (opens PubMed)
- ∅No effectStrength and muscle with a commercial 20E plus diosgenin product · No difference
RCT · n 24 · 2025 · Resistance-trained young men (Germany); 28 randomised, 24 completed
3 capsules/day as labelled · 12 weeks
Squat and bench press strength, muscle mass and muscle thickness rose in both groups with no difference between product and placebo. Lab analysis found less than 1% of the labelled 20E and 10.4% of the labelled diosgenin, and the capsules showed no muscle-cell activity.
Row on the Ecdysterone page · PubMed 40781783 (opens PubMed)