D-ribose and exercise

What 4 graded rows on d-ribose agree on for exercise, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the D-ribose page, with its PubMed record.

Your question

Supplement

D-ribose and exercise

4 rows · 70 people

Split. 1 row found an improvement, 2 found no difference and 1 had mixed results.

No difference or mixed
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.
  • Grade D× 4
Rows
4
Trials
4
People
70

Where they differ

From the rows
Who was studiedWhen published

The best-graded row, grade D, is a crossover trial of 26 people (2017) and reported mixed results.

Only the 2 rows that found no difference name athletes or trained people in their population.

The row that found an improvement is newer (2020) than the 2 rows that found no difference (2005 to 2006).

1 row with mixed results is left out of this comparison.

The rows

1 improved · 2 no difference · 1 mixed
  1. Grade DAnaerobic capacity and metabolic markers in cyclists · No difference

    Crossover RCT · n 12 · 2005 · Moderately trained male cyclists

    3 g ribose (plus 150 µg folate) before and during exercise · Single session

    No effect on repeated 30-second sprint performance or adenine nucleotide breakdown.

    Row on the D-ribose page · PubMed 16521849 (opens PubMed)

  2. Grade DSprint power (three 30-second Wingate tests) · No difference

    Crossover RCT · n 11 · 2006 · Men (USA)

    625 mg before exercise · Single dose

    No differences in peak power, mean power or power decline versus placebo.

    Row on the D-ribose page · PubMed 16937963 (opens PubMed)

  3. Grade DMuscle soreness after plyometric exercise · Improved

    RCT · n 21 · 2020 · Untrained male college students (China)

    15 g at 5 time points around exercise (1 h before to 36 h after) · 2 days around one exercise session

    Soreness at 24 and 48 hours was lower than in the D-ribose group's own first session; at 24 hours creatine kinase, LDH, myoglobin and malondialdehyde were lower than placebo. Muscle strength and antioxidant markers did not differ.

    Row on the D-ribose page · PubMed 32778175 (opens PubMed)

  4. Grade DPower output, exertion and muscle damage over repeated exercise days · Mixed

    Crossover RCT · n 26 · 2017 · Healthy adults split by fitness level (USA)

    10 g/day · 5 days (2 loading + 3 exercise days)

    In less-fit participants, mean and peak power rose and perceived exertion and creatine kinase were lower with D-ribose than dextrose; no differences in fitter participants.

    Row on the D-ribose page · PubMed 29296106 (opens PubMed)

Educational only. Not medical advice. Some links earn us a commission: kymatahealth.com/affiliate-disclosure.