Bovine colostrum and immune
What 3 graded rows on bovine colostrum agree on for immune, and where they differ. Counted side by side, never averaged.
Consensus finder Rows from the Bovine colostrum page, reviewed Oct 21, 2026 How it decides
What the rows agree on
Each block and row is one graded row from the Bovine colostrum page, with its PubMed record.
Your question
Bovine colostrum and immune
3 rows · 470 peopleSplit. 2 rows found an improvement and 1 found no difference.
- CGrade C× 2
- DGrade D× 1
- Rows
- 3
- Trials
- 12
- People
- 470
- Pooled reviews may count some twice
Where they differ
From the rowsThe best-graded row, grade C, is a meta-analysis of 239 people (2020) and found no difference.
The row that found no difference was larger: 239 people, against a median of 116 people for the 2 rows that found an improvement.
The row that found no difference is a pooled review of several trials; the 2 rows that found an improvement are single studies.
Only the 2 rows that found an improvement name men and children or teens in their population. Only the row that found no difference names athletes or trained people in its population.
The rows
2 improved · 1 no difference- CGrade CSelf-reported upper respiratory symptoms · Improved
RCT · n 174 · 2003 · Adult men in earlier double-blind exercise trials
60 g/day · 8 weeks
32% on colostrum reported respiratory symptoms in weeks 2–8 vs 48% on whey; symptom duration did not differ.
Row on the Bovine colostrum page · PubMed 12923655 (opens PubMed)
- DGrade DDays with cold symptoms in preschool children · Improved
RCT · n 57 · 2023 · Healthy preschool children
500 mg twice daily for 15 days, then 500 mg once daily for 30 days · 45 days of supplementation, followed to 21 weeks
Days with upper respiratory symptoms fell by a median 31% versus placebo, an effect that stayed significant to week 20; symptom severity fell by a median 37%. No significant side effects were reported.
Row on the Bovine colostrum page · PubMed 37630816 (opens PubMed)
- CGrade CBlood and saliva immune markers in athletes · No difference
Meta-analysis, 10 studies · n 239 · 2020 · 10 RCTs in athletes and physically active adults
Varied across trials · Varied across trials
No or fairly low effect on serum IgA and IgG, lymphocytes, neutrophils and salivary IgA.
Row on the Bovine colostrum page · PubMed 32276466 (opens PubMed)