Citrus bergamot and cholesterol
What 7 graded rows on citrus bergamot agree on for cholesterol, and where they differ. Counted side by side, never averaged.
Consensus finder Rows from the Citrus bergamot page, reviewed Oct 21, 2026 How it decides
What the rows agree on
Each block and row is one graded row from the Citrus bergamot page, with its PubMed record.
Your question
Citrus bergamot and cholesterol
7 rows · 1,216 peopleMostly an improvement: 6 of 7 rows, and most of the people. 1 found no difference.
- CGrade C× 4
- DGrade D× 3
- Rows
- 7
- Trials
- 7
- At least: a review without a trial count
- People
- 1,216
- Pooled reviews may count some twice
Where they differ
From the rowsThe best-graded row, grade C, is a meta-analysis of 615 people (2026) and found an improvement.
The 6 rows that found an improvement were larger: a median of 96 people, against 45 people for the row that found no difference.
Only the 6 rows that found an improvement include pooled reviews of several trials (1 of 6); the row that found no difference is a single study.
The best grade is C among the rows that found an improvement, and D among the row that found no difference.
The rows
6 improved · 1 no difference- CGrade CLDL cholesterol and other cardiometabolic risk factors · Improved
Meta-analysis · n 615 · 2026 · Adults, mostly with dyslipidaemia or metabolic syndrome, in 9 RCTs
Varied by trial · Varied by trial
LDL -39.5 mg/dL, total cholesterol -44.7, triglycerides -52.5, glucose -12.1, systolic blood pressure -2.1 mm Hg; HDL +5.6 mg/dL. Certainty of evidence low to very low.
Row on the Citrus bergamot page · PubMed 42746152 (opens PubMed)
- CGrade CLDL cholesterol in East Asian adults · Improved
RCT · n 102 · 2026 · East Asian adults with LDL 100–159 mg/dL
375 mg/day (150 mg flavonoids) · 4 months
LDL fell 7.0% and total cholesterol 7.3% from baseline, while placebo LDL rose 3.4%; no clinically relevant changes in liver or kidney tests, weight or blood pressure.
Row on the Citrus bergamot page · PubMed 42592560 (opens PubMed)
- CGrade CLDL cholesterol and insulin resistance in metabolic syndrome · Improved
RCT · n 90 · 2023 · Adults with features of metabolic syndrome (30 per group)
350 or 700 mg/day · 12 weeks
Both doses improved lipids and insulin sensitivity versus placebo; on 700 mg/day, LDL fell 17.7%, triglycerides 16.6%, HOMA-IR 12.2% and hs-CRP 17.9% versus baseline and placebo. Body fat and endothelial function improved only versus baseline.
Row on the Citrus bergamot page · PubMed 37732063 (opens PubMed)
- CGrade CLDL cholesterol in moderately high cholesterol · Improved
RCT · n 50 · 2023 · Healthy adults aged 18-70 with LDL 115-190 mg/dL, not on lipid drugs (Bologna, Italy)
400 mg/day · 12 weeks
In the extract group, LDL fell 7.6% from baseline (significant vs placebo), total cholesterol 7.8%, triglycerides 13.4% and apoB 8.7%, and HDL rose 4.8%; placebo LDL did not fall. No adverse events or withdrawals.
Row on the Citrus bergamot page · PubMed 37312672 (opens PubMed)
- DGrade DCholesterol and glucose in hyperlipidaemia · Improved
RCT · n 237 · 2011 · Adults with hyperlipidaemia with or without high blood glucose (Italy)
Dose not stated in the abstract · 30 days
Total and LDL cholesterol, triglycerides and blood glucose fell and HDL rose.
Row on the Citrus bergamot page · PubMed 21056640 (opens PubMed)
- DGrade DLDL cholesterol added to rosuvastatin · Improved
RCT · n 77 · 2013 · Adults with mixed hyperlipidaemia (Italy)
1,000 mg/day · 30 days
Bergamot alone lowered LDL versus placebo, and bergamot plus rosuvastatin 10 mg lowered LDL more than rosuvastatin 10 mg alone.
Row on the Citrus bergamot page · PubMed 24239156 (opens PubMed)
- DGrade DLipid, glucose and inflammatory markers in healthy adults · No difference
RCT · n 45 · 2024 · Healthy adults (Parma, Italy)
400 mL/day · 12 weeks
No difference from control in cholesterol, glucose, insulin or inflammatory markers; both groups improved over time. Well tolerated.
Row on the Citrus bergamot page · PubMed 38767145 (opens PubMed)