Chasteberry (Vitex) and PMS
What 4 graded rows on chasteberry (vitex) agree on for PMS, and where they differ. Counted side by side, never averaged.
Consensus finder Rows from the Chasteberry (Vitex) page, reviewed Oct 21, 2026 How it decides
What the rows agree on
Each block and row is one graded row from the Chasteberry (Vitex) page, with its PubMed record.
Your question
Chasteberry (Vitex) and PMS
4 rows · 1,060 peopleThey agree: all 4 rows found an improvement.
- BGrade B× 3
- CGrade C× 1
- Rows
- 4
- Trials
- 6
- People
- 1,060
- Pooled reviews may count some twice
What the rows share
From the rowsThe best-graded row, grade B, is a meta-analysis of 520 people (2019) and found an improvement.
The rows run from 162 to 520 people, published from 2001 to 2019: 1 pooled review and 3 single studies.
The rows
4 improved- BGrade BPMS remission (responder rate) · Improved
Meta-analysis, 3 studies · n 520 · 2019 · Women with PMS in double-blind trials of well-characterized extracts
As in the pooled trials · Up to 3 menstrual cycles
Women on chasteberry were 2.57 times as likely to have symptom remission as those on placebo (95% CI 1.52–4.35). Only 3 of 21 trials met reporting standards for inclusion.
Row on the Chasteberry (Vitex) page · PubMed 31780016 (opens PubMed)
- BGrade BPMS diary and PMTS scores · Improved
RCT · n 208 · 2009 · Chinese women with moderate to severe premenstrual syndrome
Extract corresponding to 40 mg of dried fruit daily · 3 menstrual cycles
PMS diary score fell by 22.7 points vs 15.5 with placebo. The authors reported a placebo effect of about 50%. No serious adverse events.
Row on the Chasteberry (Vitex) page · PubMed 19269753 (opens PubMed)
- BGrade BPMS symptom score and responder rate · Improved
RCT · n 170 · 2001 · Women with premenstrual syndrome in German community clinics (mean age 36)
One tablet daily (mg per tablet not stated in the abstract) · 3 menstrual cycles
Symptom scores (irritability, mood, anger, headache, breast fullness, bloating) improved more than with placebo; 52% vs 24% had at least a 50% drop. Mild side effects in 4 vs 3 women.
Row on the Chasteberry (Vitex) page · PubMed 11159568 (opens PubMed)
- CGrade CPMS total symptom score by dose · Improved
RCT · n 162 · 2012 · Women aged 18–45 with premenstrual syndrome
8, 20 or 30 mg/day vs placebo · 3 menstrual cycles
20 mg/day improved symptoms more than placebo and 8 mg; 30 mg was not better than 20 mg. All doses were well tolerated.
Row on the Chasteberry (Vitex) page · PubMed 23022391 (opens PubMed)