Chamomile and anxiety

What 2 graded rows on chamomile agree on for anxiety, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Chamomile page, with its PubMed record.

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Chamomile and anxiety

2 rows · 150 people

Split. 1 row found an improvement and 1 had mixed results.

Mixed
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.
  • Grade C× 1
  • Grade D× 1
Rows
2
Trials
2
People
150

What the rows share

From the rows

The best-graded row, grade C, is a randomized trial of 57 people (2009) and found an improvement.

The rows run from 57 to 93 people, published from 2009 to 2016: 2 single studies.

The rows

1 improved · 1 mixed
  1. Grade CGeneralised anxiety disorder symptoms · Improved

    RCT · n 57 · 2009 · Outpatients with mild to moderate generalised anxiety disorder

    220–1,100 mg/day (1–5 capsules, titrated) · 8 weeks

    Total Hamilton Anxiety score fell more than with placebo (p=0.047); secondary measures moved the same way; adverse events were similar.

    Row on the Chamomile page · PubMed 19593179 (opens PubMed)

  2. Grade DRelapse of generalised anxiety disorder · Mixed

    RCT · n 93 · 2016 · Responders after 12 weeks of open-label chamomile in moderate to severe generalised anxiety disorder (179 enrolled)

    500 mg three times daily (1,500 mg/day) · 12-week open-label phase, then 26 weeks randomised

    Relapse was 15.2% with continued chamomile vs 25.5% after switching to placebo (HR 0.52, not significant); anxiety symptoms stayed significantly lower with chamomile.

    Row on the Chamomile page · PubMed 27912875 (opens PubMed)

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