Capsaicin (capsaicinoids and capsinoids) and weight

What 4 graded rows on capsaicin (capsaicinoids and capsinoids) agree on for weight, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Capsaicin (capsaicinoids and capsinoids) page, with its PubMed record.

Your question

Supplement
Capsaicin (capsaicinoids and capsinoids) Choose another

Capsaicin (capsaicinoids and capsinoids) and weight

4 rows · 1,771 people

Split. 1 row found an improvement, 2 found no difference and 1 had mixed results.

No difference or mixed
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.
  • Grade C× 2
  • Grade D× 2
Rows
4
Trials
30
People
1,771
Pooled reviews may count some twice

Where they differ

From the rows
When published

The best-graded row, grade C, is a meta-analysis of 838 people (2022) and found no difference.

The row that found an improvement is newer (2023) than the 2 rows that found no difference (2003 to 2022).

1 row with mixed results is left out of this comparison.

The rows

1 improved · 2 no difference · 1 mixed
  1. Grade CBody weight and body fat (capsinoids) · No difference

    Meta-analysis, 13 studies · n 838 · 2022 · Adults in randomized trials

    Varied across trials · Varied

    No effect on weight, BMI, waist, fat mass, visceral fat or body-fat percentage overall. A subgroup of trials in overweight people lasting 12 weeks or more showed a modest weight reduction.

    Row on the Capsaicin (capsaicinoids and capsinoids) page · PubMed 36513480 (opens PubMed)

  2. Grade DWeight regain after a diet (capsaicin, 3 months) · No difference

    RCT · n 91 · 2003 · Moderately overweight adults after a 4-week very-low-energy diet

    135 mg/day · 3 months

    Weight regain did not differ from placebo (33.3% vs 19.2% of lost weight, P=0.09), though fat oxidation stayed higher with capsaicin.

    Row on the Capsaicin (capsaicinoids and capsinoids) page · PubMed 13129472 (opens PubMed)

  3. Grade CBody weight, BMI and waist in overweight adults (capsaicin) · Improved

    Meta-analysis, 15 studies · n 762 · 2023 · Overweight or obese adults in randomized trials

    Varied across trials · Varied

    Versus control, body weight fell 0.51 kg, BMI 0.25 and waist 1.12 cm; waist-to-hip ratio did not change.

    Row on the Capsaicin (capsaicinoids and capsinoids) page · PubMed 36938807 (opens PubMed)

  4. Grade DWeight and abdominal fat (capsinoids, 12 weeks) · Mixed

    RCT · n 80 · 2009 · Adults with BMI 25–35

    6 mg/day · 12 weeks

    Weight change did not differ from placebo (P=0.86), but abdominal fat fell more (−1.11% vs −0.18%, P=0.049). Fat oxidation was nearly significantly higher. Capsinoids were well tolerated.

    Row on the Capsaicin (capsaicinoids and capsinoids) page · PubMed 19056576 (opens PubMed)

Educational only. Not medical advice. Some links earn us a commission: kymatahealth.com/affiliate-disclosure.