Boswellia and joints

What 4 graded rows on boswellia agree on for joints, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Boswellia page, with its PubMed record.

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Boswellia and joints

4 rows · 1,910 people

Split. 2 rows found an improvement, 1 found no difference and 1 had mixed results.

No difference or mixed
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.
  • Grade B× 1
  • Grade C× 1
  • Grade D× 2
Rows
4
Trials
22
People
1,910
Pooled reviews may count some twice

Where they differ

From the rows
Trial sizeStudy designWhen publishedGrade

The best-graded row, grade B, is a meta-analysis of 545 people (2020) and found an improvement.

The 2 rows that found an improvement were larger: a median of 303 people, against 120 people for the row that found no difference.

Only the 2 rows that found an improvement include pooled reviews of several trials (1 of 2); the row that found no difference is a single study.

The row that found no difference is newer (2023) than the 2 rows that found an improvement (2010 to 2020).

The best grade is B among the rows that found an improvement, and D among the row that found no difference.

1 row with mixed results is left out of this comparison.

The rows

2 improved · 1 no difference · 1 mixed
  1. Grade BOsteoarthritis pain and stiffness · Improved

    Meta-analysis, 7 studies · n 545 · 2020 · People with osteoarthritis in 7 trials

    Varied across trials · Varied across trials

    VAS and WOMAC pain, stiffness and function scores improved versus placebo or comparator.

    Row on the Boswellia page · PubMed 32680575 (opens PubMed)

  2. Grade DKnee osteoarthritis pain and function · Improved

    RCT · n 60 · 2010 · Adults with knee osteoarthritis

    100 mg/day · 90 days

    Pain and function improved with both extracts versus placebo, from as early as 7 days with Aflapin.

    Row on the Boswellia page · PubMed 21060724 (opens PubMed)

  3. Grade DPersistent knee pain in adults over 40 · No difference

    RCT · n 120 · 2023 · Adults aged 40 and over with persistent knee discomfort (Spain): boswellia 29, omega-3 31, both 30, placebo 30

    4 tablets a day, each 12.5% boswellia extract (mg not stated) · 8 weeks

    Only the omega-3 product reduced pain significantly versus placebo; boswellia alone improved sleep latency, and boswellia plus omega-3 improved WOMAC quality of life.

    Row on the Boswellia page · PubMed 37686880 (opens PubMed)

  4. Grade CKnee osteoarthritis pain and function (13-trial meta-analysis) · Mixed

    Meta-analysis, 13 studies · n 1,185 · 2024 · People with knee osteoarthritis in 13 randomised trials (850 in the WOMAC analysis, 1,185 in the pain-score analysis)

    Varied across trials · Varied across trials

    Pooled WOMAC (p = 0.0865) and VAS pain scores (p = 0.3966) did not differ significantly from controls because trials varied widely; in the subgroup compared with placebo, WOMAC scores were lower with boswellia.

    Row on the Boswellia page · PubMed 39314013 (opens PubMed)

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