Black seed (Nigella sativa) and blood sugar

What 2 graded rows on black seed (nigella sativa) agree on for blood sugar, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Black seed (Nigella sativa) page, with its PubMed record.

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Black seed (Nigella sativa) and blood sugar

2 rows · 1,562 people

They agree: both rows found an improvement.

No difference
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside.
  • Grade B× 1
  • Grade D× 1
Rows
2
Trials
23
People
1,562
Pooled reviews may count some twice

What the rows share

From the rows

The best-graded row, grade B, is a meta-analysis of 1,519 people (2026) and found an improvement.

The rows run from 43 to 1,519 people, published from 2021 to 2026: 1 pooled review and 1 single study.

The rows

2 improved
  1. Grade BFasting glucose and HbA1c in metabolic disease · Improved

    Meta-analysis, 22 studies · n 1,519 · 2026 · Adults with metabolic diseases such as type 2 diabetes or obesity, in 22 trials reporting fasting glucose

    Not stated in the abstract · Not stated in the abstract

    Fasting glucose fell 18.62 mg/dL (95% CI −23.30 to −13.95) and HbA1c 0.56 points (95% CI −0.79 to −0.33) versus control; insulin and HOMA-IR did not change.

    Row on the Black seed (Nigella sativa) page · PubMed 41858302 (opens PubMed)

  2. Grade DBlood sugar, lipids and blood pressure in type 2 diabetes · Improved

    RCT · n 43 · 2021 · Adults with type 2 diabetes

    1,000 mg/day · 8 weeks

    Fasting glucose, HbA1c, total and LDL cholesterol, triglycerides, waist and blood pressure fell versus sunflower-oil placebo; HOMA-IR and HDL did not change.

    Row on the Black seed (Nigella sativa) page · PubMed 34142392 (opens PubMed)

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