Beta-glucans and colds

What 3 graded rows on beta-glucans agree on for colds, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Beta-glucans page, with its PubMed record.

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Beta-glucans and colds

3 rows · 474 people

Split. 1 row found an improvement, 1 found no difference and 1 had mixed results.

No difference or mixed
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.
  • Grade C× 2
  • Grade D× 1
Rows
3
Trials
3
People
474

Where they differ

From the rows
Who was studiedWhen publishedGrade

The best-graded row, grade C, is a randomized trial of 299 people (2019) and reported mixed results.

Only the row that found an improvement names women in its population.

The row that found no difference is newer (2017) than the row that found an improvement (2012).

The best grade is C among the row that found no difference, and D among the row that found an improvement.

1 row with mixed results is left out of this comparison.

The rows

1 improved · 1 no difference · 1 mixed
  1. Grade DUpper respiratory symptoms in stressed women · Improved

    RCT · n 77 · 2012 · Moderately stressed women

    250 mg/day · 12 weeks

    Fewer women reported upper respiratory symptoms (10% vs 29%) and mood and vigour scores were better than placebo.

    Row on the Beta-glucans page · PubMed 23378458 (opens PubMed)

  2. Grade CCold (URTI) incidence in older adults · No difference

    RCT · n 98 · 2017 · Adults aged 50–70 (49 completers per group)

    250 mg/day · 90 days in winter

    17 confirmed colds versus 28 on placebo (odds ratio 0.55, not significant); symptom days trended lower and severity did not differ.

    Row on the Beta-glucans page · PubMed 28606567 (opens PubMed)

  3. Grade CCold (URTI) incidence and symptom severity · Mixed

    RCT · n 299 · 2019 · Healthy adults with at least 3 colds in the previous year

    900 mg/day · 16 weeks in winter

    Similar numbers got a cold (71 vs 70) and overall severity did not differ, but physical symptoms were milder over the first 7 days of an episode.

    Row on the Beta-glucans page · PubMed 30198828 (opens PubMed)

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