BCAAs (branched-chain amino acids) and soreness

What 2 graded rows on bcaas (branched-chain amino acids) agree on for soreness, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the BCAAs (branched-chain amino acids) page, with its PubMed record.

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BCAAs (branched-chain amino acids) and soreness

2 rows · 392 people

They agree: both rows found an improvement.

No difference
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside.
  • Grade B× 1
  • Grade C× 1
Rows
2
Trials
26
People
392
Pooled reviews may count some twice

What the rows share

From the rows

The best-graded row, grade B, is a meta-analysis of 331 people (2024) and found an improvement.

The rows run from 61 to 331 people, published from 2019 to 2024: 2 pooled reviews and 0 single studies.

The rows

2 improved
  1. Grade BMuscle damage marker (creatine kinase) and soreness after damaging exercise · Improved

    Meta-analysis, 18 studies · n 331 · 2024 · Healthy active adults in 18 RCTs

    3.15 to 29.3 g/day (full text) · 1 to 28 days (full text)

    Creatine kinase was lower than placebo immediately (g = −0.44) and at 72 h (g = −0.99), but not at 24, 48 or 96 h; soreness was lower at 24, 48, 72 and 96 h (g = −1.82 to −0.82); lactate dehydrogenase did not change.

    Row on the BCAAs (branched-chain amino acids) page · PubMed 38625669 (opens PubMed)

  2. Grade CDelayed-onset muscle soreness · Improved

    Meta-analysis, 8 studies · n 61 · 2019 · Adults after an acute bout of exercise in 8 placebo-controlled studies

    Varied across trials · Single exercise bouts

    Soreness after exercise was lower than with placebo (effect size 0.73), based on 61 participants across 8 small studies.

    Row on the BCAAs (branched-chain amino acids) page · PubMed 30938579 (opens PubMed)

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