Avocado/Soybean Unsaponifiables (ASU) and joint structure

What 2 graded rows on avocado/soybean unsaponifiables (asu) agree on for joint structure, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Avocado/Soybean Unsaponifiables (ASU) page, with its PubMed record.

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Avocado/Soybean Unsaponifiables (ASU) and joint structure

2 rows · 453 people

Split. 1 row found no difference and 1 had mixed results.

No difference or mixed
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.
  • Grade C× 1
  • Grade D× 1
Rows
2
Trials
2
People
453

What the rows share

From the rows

The best-graded row, grade C, is a randomized trial of 345 people (2014) and reported mixed results.

The rows run from 108 to 345 people, published from 2002 to 2014: 2 single studies.

The rows

1 no difference · 1 mixed
  1. Grade DJoint-space narrowing in hip osteoarthritis over 2 years · No difference

    Pilot RCT · n 108 · 2002 · Adults with hip osteoarthritis (163 randomised, 108 radiologically evaluable)

    Not stated in the abstract · 2 years

    No overall difference in joint-space loss (intergroup p = 0.9) and no difference in clinical outcomes. A post-hoc analysis found less narrowing with ASU in the half of patients with the narrowest joints.

    Row on the Avocado/Soybean Unsaponifiables (ASU) page · PubMed 11932878 (opens PubMed)

  2. Grade CJoint-space narrowing in hip osteoarthritis over 3 years · Mixed

    RCT · n 345 · 2014 · Adults with symptomatic hip osteoarthritis (399 randomised, 345 analysed)

    300 mg/day · 3 years

    Mean joint-space loss did not differ (−0.638 vs −0.672 mm, p = 0.72), but fewer patients progressed by ≥ 0.5 mm (40% vs 50%, p = 0.040). Clinical outcomes did not differ.

    Row on the Avocado/Soybean Unsaponifiables (ASU) page · PubMed 23345601 (opens PubMed)

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