Astragalus and kidney function

What 2 graded rows on astragalus agree on for kidney function, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Astragalus page, with its PubMed record.

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Astragalus and kidney function

2 rows · 354 people

They agree: both rows found an improvement.

No difference
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside.
  • Grade C× 2
Rows
2
Trials
2
At least: a review without a trial count
People
354
Pooled reviews may count some twice

What the rows share

From the rows

The best-graded row, grade C, is a meta-analysis of 236 people (2019) and found an improvement.

The rows run from 118 to 236 people, published from 2019 to 2024: 1 pooled review and 1 single study.

The rows

2 improved
  1. Grade CAlbuminuria in diabetic kidney disease (oral preparations) · Improved

    Meta-analysis · n 236 · 2019 · People with diabetic kidney disease in 4 RCTs of oral astragalus added to conventional therapy (China)

    Varied by trial · Short term

    Albuminuria fell more than with conventional therapy alone (SMD -1.27, 95% CI -1.82 to -0.73).

    Row on the Astragalus page · PubMed 31034954 (opens PubMed)

  2. Grade CKidney function decline in diabetic kidney disease · Improved

    RCT · n 118 · 2024 · Adults with type 2 diabetes, stage 2-3 chronic kidney disease and macroalbuminuria (Hong Kong)

    15 g raw herb equivalent per day · 48 weeks

    eGFR declined 4.6 mL/min/1.73 m2 per year more slowly than with standard care alone (95% CI 1.5-7.6); albuminuria slope did not differ; endpoint systolic blood pressure was 7.9 mm Hg lower.

    Row on the Astragalus page · PubMed 38810556 (opens PubMed)

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