Arginine Alpha-Ketoglutarate (AAKG) and strength

What 3 graded rows on arginine alpha-ketoglutarate (aakg) agree on for strength, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Arginine Alpha-Ketoglutarate (AAKG) page, with its PubMed record.

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Arginine Alpha-Ketoglutarate (AAKG) and strength

3 rows · 86 people

Mostly an improvement: 2 of 3 rows, and most of the people. 1 found no difference.

No difference
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside.
  • Grade D× 2
  • No effect× 1
Rows
3
Trials
3
People
86

Where they differ

From the rows
Trial sizeWhen published

The best-graded row, grade D, is a randomized trial of 35 people (2008) and found an improvement. 1 row is graded No effect, our grade for adequately powered trials that found no effect.

The 2 rows that found an improvement were larger: a median of 35 people, against 16 people for the row that found no difference.

The row that found no difference is newer (2012) than the 2 rows that found an improvement (2006 to 2008).

The rows

2 improved · 1 no difference
  1. Grade DBench-press endurance and sprint power with a creatine blend · Improved

    RCT · n 35 · 2008 · Young men (about 23 years)

    0.075 g AAKG per kg a day with 0.1 g creatine per kg · 10 days

    Bench-press repetitions rose with the blend and with creatine alone; only the blend raised Wingate peak power (741 to 794 W). Average power did not differ.

    Row on the Arginine Alpha-Ketoglutarate (AAKG) page · PubMed 19033611 (opens PubMed)

  2. Grade DStrength, power and body composition during resistance training · Improved

    RCT · n 35 · 2006 · Resistance-trained men aged 30 to 50 (20 AAKG, 15 placebo)

    4 g three times a day (12 g a day) · 8 weeks

    The AAKG group improved 1RM bench press and Wingate peak power (P < 0.05); body composition, total body water, quadriceps endurance and aerobic capacity did not differ between groups.

    Row on the Arginine Alpha-Ketoglutarate (AAKG) page · PubMed 16928472 (opens PubMed)

  3. No effectMaximal strength and muscular endurance · No difference

    Crossover RCT · n 16 · 2012 · Eight resistance-trained and eight untrained men

    3,000 mg 45 minutes before exercise · Single dose

    1RM and total load volume on bench press and leg press did not differ from placebo in either trained or untrained men.

    Row on the Arginine Alpha-Ketoglutarate (AAKG) page · PubMed 22510253 (opens PubMed)

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