Apocynum Venetum (Luo Bu Ma) and sleep

What 2 graded rows on apocynum venetum (luo bu ma) agree on for sleep, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Apocynum Venetum (Luo Bu Ma) page, with its PubMed record.

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Apocynum Venetum (Luo Bu Ma) and sleep

2 rows · 121 people

Split. 1 row found an improvement and 1 had mixed results.

Mixed
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside. Outlined: mixed results.
  • Grade D× 2
Rows
2
Trials
2
People
121

What the rows share

From the rows

The best-graded row, grade D, is a crossover trial of 106 people (2023) and reported mixed results.

The rows run from 15 to 106 people, published from 2015 to 2023: 2 single studies.

The rows

1 improved · 1 mixed
  1. Grade DNon-REM sleep time and self-rated sleep quality · Improved

    Open-label trial · n 15 · 2015 · Adults with poor sleep (PSQI 6 or higher), mean age about 37 (Japan)

    50 mg 30 minutes before bed · 1 week per period, 1-week washout

    Non-REM sleep time rose 7.6% vs placebo (p < 0.01) on single-channel home EEG, but most of the added non-REM sleep was light sleep and delta-wave power, a marker of deep sleep, did not differ from placebo. The PSQI improvement with the extract was only a non-significant trend (p = 0.10).

    Row on the Apocynum Venetum (Luo Bu Ma) page · PubMed 26052150 (opens PubMed)

  2. Grade DSelf-rated sleep problems (OSA sleep questionnaire) · Mixed

    Crossover RCT · n 106 · 2023 · Healthy, non-depressed full-time workers with poor sleep (PSQI above 5), Japan; 160 enrolled, 106 analysed

    50 mg/day · 7 days per period, washouts of at least 7 days

    Sleep-questionnaire scores improved from baseline during the extract week, but they also improved during the placebo and mindfulness weeks. Each period was compared with baseline only; the extract was not tested directly against placebo.

    Row on the Apocynum Venetum (Luo Bu Ma) page · PubMed 37242260 (opens PubMed)

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