Anise (Aniseed) and functional dyspepsia

What 2 graded rows on anise (aniseed) agree on for functional dyspepsia, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the Anise (Aniseed) page, with its PubMed record.

Your question

Anise (Aniseed) and functional dyspepsia

2 rows · 214 people

They agree: both rows found an improvement.

No difference
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside.
  • Grade C× 2
Rows
2
Trials
2
At least: a review without a trial count
People
214
Pooled reviews may count some twice

What the rows share

From the rows

The best-graded row, grade C, is a systematic review of 107 people (2023) and found an improvement.

The rows run from 107 people, published from 2015 to 2023: 1 pooled review and 1 single study.

The rows

2 improved
  1. Grade CFunctional dyspepsia global symptoms (Cochrane review) · Improved

    Systematic review · n 107 · 2023 · Adults with functional dyspepsia; the review covered 41 trials of 27 herbal medicines (4477 people), one of them on anise

    As in the included trial · As in the included trial

    Anise improved dyspepsia symptoms vs placebo (SMD -2.30, 95% CI -2.79 to -1.80; 1 study, 107 participants), rated low-certainty evidence.

    Row on the Anise (Aniseed) page · PubMed 37323050 (opens PubMed)

  2. Grade CFunctional dyspepsia (postprandial distress) severity · Improved

    RCT · n 107 · 2015 · Adults aged 18 to 65 with postprandial distress syndrome (Rome III)

    3 g after each meal, three times daily (9 g/day) · 4 weeks, follow-up to week 12

    Symptom scores fell from 10.6 to 2.44 at week 4 on anise vs a rise from 10.96 to 13.05 on placebo (P = 0.0001), with the gap persisting at week 12.

    Row on the Anise (Aniseed) page · PubMed 25767516 (opens PubMed)

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