American ginseng and fatigue

What 3 graded rows on american ginseng agree on for fatigue, and where they differ. Counted side by side, never averaged.

What the rows agree on

Each block and row is one graded row from the American ginseng page, with its PubMed record.

Your question

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American ginseng and fatigue

3 rows · 452 people

Split. 1 row found an improvement and 2 found no difference.

No difference
Improved
Each block is one evidence row, sized by how many people it enrolled, with its grade inside.
  • Grade C× 1
  • Grade D× 2
Rows
3
Trials
3
People
452

Where they differ

From the rows
Trial sizeGrade

The best-graded row, grade C, is a randomized trial of 364 people (2013) and found an improvement.

The row that found an improvement was larger: 364 people, against a median of 44 people for the 2 rows that found no difference.

The best grade is C among the row that found an improvement, and D among the rows that found no difference.

The rows

1 improved · 2 no difference
  1. Grade DFatigue in multiple sclerosis · No difference

    Crossover RCT · n 56 · 2011 · Adults with multiple sclerosis and fatigue

    100, 200 then 400 mg/day (escalating) · 6 weeks

    Fatigue Severity Scale scores did not differ from placebo; no serious adverse events.

    Row on the American ginseng page · PubMed 21803872 (opens PubMed)

  2. Grade DFatigue in head and neck cancer survivors · No difference

    RCT · n 32 · 2020 · Adults at least 1 year after curative treatment for head and neck cancer with fatigue score above 4

    1,000 mg/day · 8 weeks

    Fatigue scores at 8 weeks did not differ from placebo (mean 4.6 vs 3.4, not significant).

    Row on the American ginseng page · PubMed 32617701 (opens PubMed)

  3. Grade CCancer-related fatigue · Improved

    RCT · n 364 · 2013 · Fatigued cancer survivors at 40 US institutions

    2,000 mg/day · 8 weeks

    General fatigue improved 14.4 vs 8.2 points at 4 weeks (P = .07, primary endpoint not met) and 20 vs 10.3 points at 8 weeks (P = .003); toxicities did not differ from placebo.

    Row on the American ginseng page · PubMed 23853057 (opens PubMed)

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