Botanical

Cinnamon

Also called Cinnamomum cassia, Cinnamomum verum, Ceylon cinnamon, cassia

By Kymata Labs EditorialMedical review pendingLast reviewed October 11, 2026 · What changed

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Summary

Cinnamon is sold for blood sugar. A Cochrane review of 10 trials (577 people) found insufficient evidence, while a meta-analysis of 10 trials in type 2 diabetes found lower fasting glucose and lipids but no change in HbA1c. Trials differ widely. Cassia cinnamon contains coumarin, which has been linked to liver problems.

Top graded outcomes:C evidence grade Fasting glucose and lipids in type 2 diabetesC evidence grade HbA1c and glucose in diabetes

Key facts

Two types
Cassia (most supplements) and Ceylon ("true") cinnamon; cassia contains more coumarin[1]
Fasting glucose
About 25 mg/dL lower in a 10-trial analysis, with very high heterogeneity[2]
HbA1c
No significant change in that analysis or in the Cochrane review[2][3]
Liver
Interactions between coumarin in cassia and the liver have been reported[1]
Evidence base
2 graded human outcomes on this page
Last reviewed
October 11, 2026

How it works

ProposedAnimal studies suggest cinnamon may improve glycaemic control; how it would act in people has not been established.[3]

What the human research says

Human trials only, one row per outcome. The form column shows what each trial actually tested. Grades follow our evidence-grading policy.

Form tested
Sort

Showing 2 of 2 outcomes. Human trials only.

OutcomeEffectGradeBest evidencePMID
HbA1c and glucose in diabetesNo effectGrade C

Systematic review · n = 577 · 2012

People with type 1 or type 2 diabetes in 10 trials

Form: Cinnamon monopreparations (mainly cassia) · Dose: Mean 2 g/day · Duration: 4–16 weeks

No significant difference in HbA1c, insulin or post-meal glucose; the fasting glucose effect was inconclusive. Most trials had high or unclear risk of bias.

22972104 (opens PubMed)Source [3]
Fasting glucose and lipids in type 2 diabetesImprovedGrade C

Meta-analysis · n = 543 · 2013

Adults with type 2 diabetes in 10 trials

Form: Cinnamon (mostly cassia) · Dose: 120 mg to 6 g/day · Duration: 4–18 weeks

Fasting glucose fell 24.6 mg/dL, total cholesterol 15.6, LDL 9.4 and triglycerides 29.6 mg/dL versus control, and HDL rose 1.7 mg/dL; HbA1c did not change.

24019277 (opens PubMed)Source [2]

Forms

FormElemental %Absorption (human data)GI toleranceStudied for
Cassia cinnamon (Cinnamomum cassia / aromaticum)VariesNot applicable (whole compound or extract; no elemental fraction)No head-to-head human absorption data in the sources cited here.Contains coumarin; liver interactions have been reported.[1]Most diabetes trials
Ceylon cinnamon (Cinnamomum verum)VariesNot applicable (whole compound or extract; no elemental fraction)No head-to-head human absorption data in the sources cited here.Contains only trace coumarin.[1]Few trials

Studied doses

Doses studied in human trials ranged from 120 mg to 6 g of cinnamon per day for 4–18 weeks, with a mean of about 2 g/day in the Cochrane review.[2][3]

These are amounts used in research, not personal advice. Your clinician or pharmacist can say what fits you.

Interactions

Published interactions only: each row cites a source. No row means none was found in our sources, not that a combination is safe.

Medicines

  • Some anticancer medicines and nicotineNIH fact sheetNCCIH notes some components of cinnamon may interact with an anticancer medicine or with nicotine.[1]

Who should be careful

Liver conditions (cassia)
Coumarin in cassia cinnamon has been linked to liver problems.[1]
Breastfeeding
Little is known about larger amounts of Ceylon or cassia cinnamon while breastfeeding.[1]
People on diabetes medicines
Trials were small and inconsistent; changes to diabetes care belong with your clinician.[3]

Talk to your pharmacist or clinician before starting a supplement, especially if you take prescription medicines.

Frequently asked questions

Does cinnamon lower blood sugar?

One meta-analysis found lower fasting glucose but no HbA1c change; Cochrane judged the evidence insufficient.[2][3]

Cassia or Ceylon?

Most supplements and trials use cassia, which has more coumarin; Ceylon has only trace amounts.[1]

Is cinnamon safe for the liver?

Food amounts are likely safe; NCCIH notes liver interactions with coumarin in cassia.[1]

How much was used in trials?

From 120 mg to 6 g a day, averaging about 2 g, for up to 18 weeks.[2][3]

Sources

  1. [1]Cinnamon. National Center for Complementary and Integrative Health (NCCIH), 2024. fact-sheet
  2. [2]Cinnamon use in type 2 diabetes: an updated systematic review and meta-analysis.. Ann Fam Med, 2013. meta-analysis PMID 24019277
  3. [3]Cinnamon for diabetes mellitus.. Cochrane Database Syst Rev, 2012. systematic-review PMID 22972104

What changed

  1. October 11, 2026 · all · new page (encyclopedia expansion, A–L)First draft. Every PMID checked against NCBI E-utilities (title, journal and year taken from the PubMed record) and each evidence row written from its PubMed abstract; self-reviewed in a separate adversarial pass.Writer: Kymata Labs Editorial · No credentialed reviewer yet

How we write, grade and correct these pages: editorial and evidence policy.

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